Etomidate

Drug ingredientActive Shortage

CAS 33125-97-2

This drug ingredient is in active FDA shortage. At least one manufacturer cannot meet demand.

US productionNot reported

Import value, 2024$114M

Top sourceChina 26%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293329 · basket

These shares come from HS customs code 293329, which covers 173 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 26%ChinaIN 17%IndiaKR 16%South KoreaDE 9%GermanyIT 9%Italy

Australia
Brazil
Czech Republic
Ireland
Sweden
Ukraine
Poland
United Arab Emirates
Hungary
Israel
Netherlands
Canada
Saudi Arabia
Greece
Belgium
Austria
Latvia
Singapore
Denmark

15 FDA-registered drug labelers

Armas Pharmaceuticals Inc.

Bachem SA, succursale de Vionnaz

Caplin Steriles Limited

Civica, Inc.

Eugia US LLC

Fosun Pharma USA Inc

Fresenius Kabi USA, LLC

Gland Pharma Limited

Henry Schein, Inc.

HF Acquisition Co LLC, DBA HealthFirst

Hikma Pharmaceuticals USA Inc.

Hospira, Inc.

Huzhou Zhanwang Pharmaceutical Co., Ltd.

Mylan Institutional LLC

Pisgah Labs, Incorporated

Why It Matters

Sectors

Health

Downstream Uses

Appears in 4 drug and cosmetic product listings (FDA).

•Etomidate
•Etomidate injection, solution
•Amidate
•Amidate(TM) Etomidate

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

Active Shortage

Shortage History

Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.

Current shortage
Etomidate Injection
Shortage listed since October 5, 2022
Manufacturer reports: 1 unavailable, 1 available

See all current drug shortages

Chemical Identity

CAS33125-97-2

PubChem CID667484

DTXSIDDTXSID5023033

FormulaC14H16N2O2

Mol. Weight244.29 g/mol

SMILESCCOC(=O)C1=CN=CN1C(C)C2=CC=CC=C2

Data Sources

PubChem · compound 667484Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA Drug ShortagesRetrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Etomidate (CAS 33125-97-2) https://chemicalindependence.com/chemical/33125-97-2/ PubChem: 667484. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/667484 FDA National Drug Code directory: CAS 33125-97-2. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 33125-97-2. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293329 for CAS 33125-97-2. Reporting year: 2024. https://usatrade.census.gov/