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Leucine

Drug ingredient

CAS 328-39-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 328-39-2
US productionNot reported
Import value, 2024$503M
Top sourceChina 25%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292249 · basket

These shares come from HS customs code 292249, which covers 170 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 25%ChinaIN 17%IndiaSG 13%SingaporeIT 9%ItalyCH 7%Switzerland
18 FDA-registered drug labelers
Ajinomoto Health & Nutrition North America Inc.
B. Braun Medical Inc.
Baxter Healthcare Company
Baxter Healthcare Corporation
BioActive Nutritional, Inc.
Deseret Biologicals, Inc.
Energique, Inc.
Fresenius Kabi USA, LLC
Guna spa
ICU Medical Inc.
Liddell Laboratories, Inc.
Nutritional Specialties, Inc.
PharmaZell GmbH
Professional Complementary Health Formulas
Professional Compounding Centers of America
Shanghai Ajinomoto Amino Acid Co., Ltd.
Shanghai Plumino Amino Acid Co., Ltd.
Temple Health Nutrition, LLC

Why It Matters

Sectors
Health
Downstream Uses

Appears in 23 drug and cosmetic product listings (FDA).

  • •Aminosyn-PF
  • •Electrolyte Plus
  • •Strength F
  • •Plenamine
  • •Kabiven
  • •Clinimix
  • •L-Leucine High 7414
  • •Clinimix E
Show all 23
  • •Clinisol
  • •Strength M
  • •ProSol
  • •TrophAmine
  • •TH-101
  • •Aminosyn II
  • •Metabatone
  • •Vital Skin Hair Nails
  • •Osteobios
  • •Travasol
  • •Recovatone
  • •Perikabiven
  • •ANTI AGE SKIN
  • •Metab
  • •Premasol - sulfite-free (Amino Acid)
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.16/gAaron Chemicals LLC
CountryHong Kong
Pack$79.00 / 500 g
Purity98%
Vendors24 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

23 more vendors
VendorCountry$/gPackPurity
Angene ChemicalChina → Hong Kong$0.17500 g98%
A2B Chem LLCUnited States$0.271 kg98%
Acrotein ChemBio, Inc.United States$0.281 kg—
AA BLOCKSUnited States$0.291 kg98%
Combi-Blocks, Inc.United States$0.30500 g98%
Fluorochem EUGermany$0.38100 g98%
AK Scientific SpecializedUnited States$0.43100 g95%
AK Scientific, Inc.United States$0.57100 g98%
BLD Pharmatech GmbHGermany$0.711 kg97%
BLD Pharmatech Ltd.China$0.711 kg97%
BLD Pharmatech Co., LimitedUnited States$0.84500 g97%
Ambeed, Inc.United States$0.84500 g97%
MedChemExpress MCESweden$1.05100 g99.95%
Angene International LimitedUnited States$1.23100 g98%
Sigma-Aldrich (Rush Stock)Germany$6.2525 g99%
Sigma-AldrichGermany$6.2525 g99%
TargetMol ChemicalsChina → United States$29.001 g98.66%
MolnovaChina$74.00500 mg99%
Labotest KGGermany$217.805000 mg90%
Otava, Ltd.Ukraine$460.00250 mg90%
Otava, Ltd. (2 weeks)Ukraine$2724.0050 mg90%
AngeneChina → Hong Kong$4266.6730 mg98%
Key Organics Ltd.United Kingdom$6900.0010 mg98%

Chemical Identity

CAS328-39-2
PubChem CIDNot recorded
DTXSIDDTXSID00859050
FormulaC6H13NO2
Mol. Weight131.175 g/mol
SMILESCC(C)CC(N)C(O)=O

Data Sources

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Brief citations

Leucine (CAS 328-39-2) https://chemicalindependence.com/chemical/328-39-2/ EPA TSCA Inventory: CAS 328-39-2. Retrieved 2026-10-04. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: CAS 328-39-2. Retrieved 2026-10-04. https://open.fda.gov/data/ndc/ US Census international trade: HS 292249 for CAS 328-39-2. Reporting year: 2024. https://usatrade.census.gov/