Ethene, 1,1'-[methylenebis(sulfonyl)]bis-

CAS 3278-22-6

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$760M

Top sourceChina 33%

At least one company claimed its 2019 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2019. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293090 · basket

EPA reports by year

2019: US production Confidential · Imports Confidential

These shares come from HS customs code 293090, which covers 418 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 33%ChinaES 14%SpainCH 9%SwitzerlandIT 7%ItalyIN 7%India

Israel
Croatia
Ukraine
Slovakia
United Arab Emirates
Ireland
Poland
Lithuania
Brazil
Singapore
Australia
Armenia
Hong Kong
Vietnam
Czech Republic
Hungary
Greece
Russia

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Eastman Kodak

Why It Matters

Sectors

Consumer Products

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Hardener in Photographic Film, Paper, Plate, and Chemical Manufacturing (100%)Processing—incorporation into article

Vendor Pricing

$1.44/gCombi-Blocks, Inc.

CountryUnited States

Pack$720.00 / 500 g

Purity98%

Vendors13 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

12 more vendors

Vendor	Country	$/g	Pack	Purity
A2B Chem LLC	United States	$1.53	500 g	98%
AA BLOCKS	United States	$1.61	500 g	98%
Aaron Chemicals LLC	Hong Kong	$2.14	500 g	98%
Angene Chemical	China → Hong Kong	$2.28	500 g	98%
AK Scientific Specialized	United States	$2.40	100 g	95%
Ambeed, Inc.	United States	$3.20	25 g	98%
AK Scientific, Inc.	United States	$3.21	100 g	97%
Angene International Limited	United States	$4.04	100 g	95%
Synthonix	United States	$5.00	10 g	98%
Fluorochem EU	Germany	$10.89	1 g	97%
AstaTech (2 weeks)	United States	$40.00	1 g	95%
Angene	China → Hong Kong	$4266.67	30 mg	98%

Chemical Identity

CAS3278-22-6

PubChem CID76764

DTXSIDDTXSID8062947

FormulaC5H8O4S2

Mol. Weight196.2 g/mol

SMILESC=CS(=O)(=O)CS(=O)(=O)C=C

Data Sources

EPA CompTox (DSSTox) · DTXSID8062947Retrieved 2026-04-06
PubChem · compound 76764Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Ethene, 1,1'-[methylenebis(sulfonyl)]bis- (CAS 3278-22-6) https://chemicalindependence.com/chemical/3278-22-6/ EPA CompTox (DSSTox): DTXSID8062947. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID8062947 PubChem: 76764. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/76764 EPA Chemical Data Reporting: 3278-22-6. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 3278-22-6. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293090 for CAS 3278-22-6. Reporting year: 2024. https://usatrade.census.gov/