Calcitriol

Drug ingredient

CAS 32222-06-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$295M

Top sourceChina 56%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293629 · basket

These shares come from HS customs code 293629, which covers 17 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 56%ChinaCH 12%SwitzerlandIN 12%IndiaIT 11%ItalyJP 2%Japan

Spain
Netherlands
Czech Republic
Israel
Guyana
Norway
Australia
Taiwan
Ivory Coast
Honduras
South Korea
Austria
Colombia
Brazil
Mexico
Belgium
South Africa
Turkey
Hong Kong
Chile
Slovenia
Ecuador
Sweden
Vietnam

30 FDA-registered drug labelers

A-S Medication Solutions

American Health Packaging

Amneal Pharmaceuticals LLC

Aphena Pharma Solutions - Tennessee, LLC

Assia Chemical Industries Ltd - Teva Tech Site

BIONPHARMA INC.

Bryant Ranch Prepack

CARBOGEN AMCIS B.V.

Cardinal Health 107, LLC

Catalent Germany Eberbach GmBH

Catalent Pharma Solutions, LLC

Cerbios-Pharma SA

Chartwell RX, LLC

Corden Pharma Colorado, Inc.

Formosa Laboratories, Inc.

FOSUN PHARMA USA INC

Galderma Laboratories, L.P.

Gland Pharma Limited

Golden State Medical Supply, Inc.

Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.

Hikma Pharmaceuticals USA Inc.

MicroBiopharm Japan Co., Ltd

Padagis Israel Pharmaceuticals Ltd

Patheon Softgels Inc

Patrin Pharma, Inc

PD-Rx Pharmaceuticals, Inc.

Rising Pharma Holdings, Inc.

Strides Pharma Science Limited

Sun Pharmaceutical Industries, Inc.

Teva Pharmaceuticals USA, Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Calcitriol
•Vectical

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No Shortage

Shortage History

Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.

to be discontinued
Calcitriol Capsule
Shortage listed since December 4, 2025

See all current drug shortages

Chemical Identity

CAS32222-06-3

PubChem CID5280453

DTXSIDDTXSID5022722

FormulaC27H44O3

Mol. Weight416.6 g/mol

SMILESCC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C

Data Sources

PubChem · compound 5280453Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA Drug ShortagesRetrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Calcitriol (CAS 32222-06-3) https://chemicalindependence.com/chemical/32222-06-3/ PubChem: 5280453. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5280453 FDA National Drug Code directory: CAS 32222-06-3. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 32222-06-3. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293629 for CAS 32222-06-3. Reporting year: 2024. https://usatrade.census.gov/