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Bupropion hydrochloride

Drug ingredient

CAS 31677-93-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 31677-93-7
1 HCl
US productionNot reported
Import value, 2024$21M
Top sourceIndia 59%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292239 · basket

These shares come from HS customs code 292239, which covers 30 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IN 59%IndiaDE 15%GermanyCN 14%ChinaIT 10%ItalyES 2%Spain
88 FDA-registered drug labelers
A-S Medication Solutions
Aarti Pharmalabs Limited
Accord Healthcare Inc.
Actavis Pharma, Inc.
Advanced Rx of Tennessee, LLC
Advanced Rx Pharmacy of Tennessee, LLC
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
Alivus Life Sciences Limited
American Health Packaging
Amneal Pharmaceuticals of New York LLC
Aphena Pharma Solutions - Tennessee, LLC
Apnar Pharma LP
Apotex Corp
Asclemed USA, Inc.
Aurobindo Pharma Limited
AvPAK
Axsome Therapeutics, Inc.
Bausch Health US LLC
BluePoint Laboratories
Bryant Ranch Prepack
Cadila Pharmaceuticals Limited
Camber Pharmaceuticals, Inc.
Cardinal Health 107, LLC
Chartwell RX, LLC
Chemeca Drugs Private Limited
CIPLA USA INC.,
Coupler LLC
Darmerica, LLC
Derivados Quimicos
Dipharma Francis Srl
DIRECT RX
Divi's Laboratories Limited
Dr Reddys Laboratories Inc
Epic Pharma LLC
Erregierre SpA
Exelan Pharmaceuticals Inc.
GlaxoSmithKline LLC
Golden State Medical Supply, Inc.
Granules India Limited
Granules Pharmaceuticals Inc.
HAWAII REPACK, INC.
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
Hetero Drugs Limited
HIKAL LIMITED
Ipca Laboratories Limited
Jubilant Biosys limited
Lannett Company Inc.
LETCO MEDICAL, LLC
Lupin Pharmaceuticals, Inc.
MAJOR PHARMACEUTICALS
Micro Labs Limited
Modavar Pharmaceuticals LLC
Mullan Pharmaceutical Inc.
Nalpropion Pharmaceuticals LLC
NCS HealthCare of KY, LLC dba Vangard Labs
Northwind Health Company, LLC
NuCare Pharmaceuticals, Inc.
NuCare Pharmacueticals, Inc.
Olon SpA
Oryza pharmaceuticals Inc.
Patheon Inc.
PD-Rx Pharmaceuticals, Inc.
Pharma Source Direct, Inc.
Preferred Pharmaceuticals Inc.
Professional Compounding Centers of America
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
Quality Care Products, LLC
Quallent Pharmaceuticals Health LLC
RADHA PHARMACEUTICALS, INC.
REMEDYREPACK INC.
Rising Pharma Holdings, Inc.
ScieGen Pharmaceuticals, Inc.
Slate Run Pharmaceuticals, LLC
Solco Healthcare US LLC
Spectrum Chemicals and Laboratory Products
ST. MARY'S MEDICAL PARK PHARMACY
SUN PHARMACEUTICAL INDUSTRIES, INC.
TWi Pharmaceuticals, Inc.
Upsher-Smith Laboratories, LLC
Vitruvias Therapeutics
Westminster Pharmaceuticals, LLC
Willow Birch Pharma, LLC
Zhejiang Apeloa Jiayuan Pharmaceutical Co., Ltd.
Zhejiang Supor Pharmaceuticals Co., Ltd
Zydus Lifesciences Limited
Zydus Pharmaceuticals USA Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 11 drug and cosmetic product listings (FDA).

  • •Bupropion hydrochloride
  • •Bupropion Hydrochloride SR
  • •Bupropion Hydrochloride (XL)
  • •Bupropion HCL ER (XL)
  • •Auvelity
  • •bupropion
  • •Forfivo XL
  • •Wellbutrin XL
Show all 11
  • •Bupropion HCL
  • •Wellbutrin SR
  • •Contrave Extended-Release
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS31677-93-7
PubChem CID62884
DTXSIDDTXSID6044561
FormulaC13H19Cl2NO
Mol. Weight276.2 g/mol
SMILESCC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C.Cl

Data Sources

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Brief citations

Bupropion hydrochloride (CAS 31677-93-7) https://chemicalindependence.com/chemical/31677-93-7/ PubChem: 62884. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/62884 FDA National Drug Code directory: CAS 31677-93-7. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292239 for CAS 31677-93-7. Reporting year: 2024. https://usatrade.census.gov/