Allopurinol

Drug ingredient

CAS 315-30-0

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$7.6B

Top sourceIreland 61%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India

Israel
Bulgaria
Japan
Spain
Sweden
Canada
Taiwan
Finland
Portugal
Mexico
Belgium
Hungary
Austria
Brazil
Ukraine
Croatia
Malta
South Korea
South Africa
Denmark
Czech Republic
Malaysia
Argentina
Poland
Cameroon
Australia
Hong Kong
Slovakia
Latvia

56 FDA-registered drug labelers

A-S Medication Solutions

Accord Healthcare Inc.

Actavis Pharma, Inc.

Advanced Rx of Tennessee, LLC

Advanced Rx Pharmacy of Tennessee, LLC

American Health Packaging

Aphena Pharma Solutions - Tennessee, LLC

Aurobindo Pharma Limited

Bryant Ranch Prepack

Camber Pharmaceuticals, Inc.

Cardinal Health 107, LLC

Chartwell RX, LLC

Coupler LLC

Dasami Lab Private Limited

Direct_Rx

Dr. Reddy's Laboratories Limited

Exemed Pharmaceuticals

Florida Pharmaceutical Products, LLC

Hainan Poly Pharm. Co., Ltd.

Haleos Labs Limited

Harman Finochem Limited

Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.

Hetero Drugs Limited

Indoco Remedies Limited

IOL Chemicals and Pharmaceuticals Ltd.

Ipca Laboratories Limited

Leading Pharma, LLC

Major Pharmaceuticals

Mylan Institutional Inc.

Mylan Pharmaceuticals Inc.

NCS HealthCare of KY, LLC dba Vangard Labs

NorthStar RxLLC

Northwind Health Company, LLC

NuCare Pharmaceuticals, Inc.

Par Health USA, LLC

PD-Rx Pharmaceuticals, Inc.

Preferred Pharmaceuticals Inc.

Professional Compounding Centers of America

Professional Compounding Centers of America dba PCCA

Proficient Rx LP

Redpharm Drug

REMEDYREPACK INC.

Rising Pharma Holdings, Inc.

Safecor Health, LLC

SICOR Societa' Italiana Corticosteroidi s.r.l.

Spectrum Laboratory Products, Inc.

ST. MARY'S MEDICAL PARK PHARMACY

Sun Pharmaceutical Industries, Inc.

Supriya Lifescience Limited

Unichem Laboratories Limited, India

Unichem Pharmaceuticals (USA), Inc.

Uquifa Spain

Willow Birch Pharma, LLC

XLCare Pharmaceuticals Inc.

Zydus Lifesciences Limited

Zydus Pharmaceuticals (USA) Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Allopurinol

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No Shortage

Shortage History

Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.

to be discontinued
Allopurinol Tablet
Shortage listed since February 19, 2026

See all current drug shortages

Vendor Pricing

$0.09/gAaron Chemicals LLC

CountryHong Kong

Pack$47.00 / 500 g

Purity97%

Vendors8 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

7 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.11	500 g	97%
A2B Chem LLC	United States	$0.26	100 g	98%
AA BLOCKS	United States	$0.31	100 g	98%
Combi-Blocks, Inc.	United States	$0.36	1 kg	97%
Cayman Europe	Estonia	$1.76	100 g	98%
Angene International Limited	United States	$2.84	25 g	98%
Angene	China → Hong Kong	$4266.67	30 mg	97%

Chemical Identity

CAS315-30-0

PubChem CID135401907

DTXSIDDTXSID4022573

FormulaC5H4N4O

Mol. Weight136.11 g/mol

SMILESC1=NNC2=C1C(=O)NC=N2

Data Sources

PubChem · compound 135401907Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA Drug ShortagesRetrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Allopurinol (CAS 315-30-0) https://chemicalindependence.com/chemical/315-30-0/ PubChem: 135401907. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/135401907 EPA TSCA Inventory: CAS 315-30-0. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA Drug Shortages: CAS 315-30-0. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293359 for CAS 315-30-0. Reporting year: 2024. https://usatrade.census.gov/