Ibuprofen sodium

Drug ingredient

CAS 31121-93-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 31121-93-4 — 2 H₂O · 1 Na⁺

US productionNot reported

Import value, 2024$84M

Top sourceChina 63%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291639 · basket

These shares come from HS customs code 291639, which covers 229 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 63%ChinaIT 19%ItalyIN 8%IndiaDE 4%GermanyCH 3%Switzerland

Spain
Ukraine
Singapore
Turkey
Norway
Czech Republic
Taiwan
South Korea
Japan
Mexico
New Zealand
Canada
Sweden
Hong Kong
Latvia

6 FDA-registered drug labelers

BASF Corporation

Haleon US Holdings LLC

Hubei Biocause Heilen Pharmaceutical Co., Ltd

Shandong Xinhua Pharmaceutical Company Limited

SMS Pharmaceuticals Limited

SOLARA ACTIVE PHARMA SCIENCES LIMITED

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Advil
•Advil Menstrual Pain

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS31121-93-4

PubChem CID23690315

DTXSIDDTXSID4040501

FormulaC13H21NaO4

Mol. Weight264.29 g/mol

SMILESCC(C)CC1=CC=C(C=C1)C(C)C(=O)[O-].O.O.[Na+]

Data Sources

PubChem · compound 23690315Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Ibuprofen sodium (CAS 31121-93-4) https://chemicalindependence.com/chemical/31121-93-4/ PubChem: 23690315. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/23690315 FDA National Drug Code directory: CAS 31121-93-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291639 for CAS 31121-93-4. Reporting year: 2024. https://usatrade.census.gov/