Cyclizine hydrochloride

Drug ingredient

CAS 303-25-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$7.6B

Top sourceIreland 61%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India

Israel
Bulgaria
Japan
Spain
Sweden
Canada
Taiwan
Finland
Portugal
Mexico
Belgium
Hungary
Austria
Brazil
Ukraine
Croatia
Malta
South Korea
South Africa
Denmark
Czech Republic
Malaysia
Argentina
Poland
Cameroon
Australia
Hong Kong
Slovakia
Latvia

1 FDA-registered drug labeler

Srikem Laboratories Pvt. Ltd.

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$139.60/gA2B Chem LLC

CountryUnited States

Pack$698.00 / 5 g

Purity98%

Vendors7 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

6 more vendors

Vendor	Country	$/g	Pack	Purity
AA BLOCKS	United States	$155.00	5 g	98%
Cayman Europe	Estonia	$222.05	5 g	98%
Molnova	China	$285.00	200 mg	99%
Aaron Chemicals LLC	Hong Kong	$442.00	1 g	98%
Angene Chemical	China → Hong Kong	$446.00	1 g	98%
MedChemExpress MCE	Sweden	$554.18	1 g	99.9%

Chemical Identity

CAS303-25-3

PubChem CID6420019

DTXSIDDTXSID2047773

FormulaC18H23ClN2

Mol. Weight302.8 g/mol

SMILESCN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=CC=C3.Cl

Data Sources

PubChem · compound 6420019Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Cyclizine hydrochloride (CAS 303-25-3) https://chemicalindependence.com/chemical/303-25-3/ PubChem: 6420019. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6420019 FDA National Drug Code directory: CAS 303-25-3. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293359 for CAS 303-25-3. Reporting year: 2024. https://usatrade.census.gov/