1,2-Benzenedicarboxylic acid, 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]bis-

CAS 3016-76-0

Used in 1 industrial sector tracked by the EPA.

US productionNot reported

Import value, 2024$316M

Top sourceSouth Korea 19%

EPA lists this chemical for 2023 but publishes zero or no volume for both production and imports.

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291739 · basket

EPA reports by year

2023: US production Not published · Imports Not published

These shares come from HS customs code 291739, which covers 103 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

KR 19%South KoreaCN 19%ChinaIN 18%IndiaES 13%SpainCA 9%Canada

Netherlands
Malaysia
Colombia
Switzerland
Turkey
Germany
Peru
Brazil
Sweden
Belgium
Denmark
Czech Republic
Ukraine
Hong Kong

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Kansas Holdco 1

Why It Matters

Sectors

Core Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant

Vendor Pricing

$1.12/gAaron Chemicals LLC

CountryHong Kong

Pack$559.00 / 500 g

Purity97%

Vendors18 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

17 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$1.20	500 g	98%
A2B Chem LLC	United States	$1.40	25 g	98%
AA BLOCKS	United States	$1.60	25 g	98%
Combi-Blocks, Inc.	United States	$1.65	100 g	97%
Chemscene	United States	$1.85	100 g	—
BLD Pharmatech Co., Limited	United States	$1.85	100 g	97%
BLD Pharmatech GmbH	Germany	$1.85	100 g	97%
BLD Pharmatech Ltd.	China	$1.85	100 g	97%
Ambeed, Inc.	United States	$1.85	100 g	97%
AK Scientific Specialized	United States	$2.00	25 g	95%
AK Scientific, Inc.	United States	$2.80	25 g	98%
MedChemExpress MCE	Sweden	$2.81	100 g	98.98%
AstaTech (2 weeks)	United States	$3.83	100 g	95%
Synthonix	United States	$4.50	10 g	97%
Angene International Limited	United States	$5.72	25 g	98%
Life Chemicals Inc.	Ukraine → Canada	$4200.00	50 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	98%

Chemical Identity

CAS3016-76-0

PubChem CIDNot recorded

DTXSIDDTXSID8062789

FormulaC19H10F6O8

Mol. Weight480.271 g/mol

SMILESOC(=O)C1=CC=C(C=C1C(O)=O)C(C1=CC(C(O)=O)=C(C=C1)C(O)=O)(C(F)(F)F)C(F)(F)F

Data Sources

EPA TSCA InventoryRetrieved 2026-04-29
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

1,2-Benzenedicarboxylic acid, 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]bis- (CAS 3016-76-0) https://chemicalindependence.com/chemical/3016-76-0/ EPA TSCA Inventory: CAS 3016-76-0. Retrieved 2026-04-29. https://www.epa.gov/tsca-inventory EPA Chemical Data Reporting: 3016-76-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 3016-76-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291739 for CAS 3016-76-0. Reporting year: 2024. https://usatrade.census.gov/