Diammonium citrate

CAS 3012-65-5

U.S. production volumes are classified as confidential business information.

Molecular structure of 3012-65-5 — 2 NH₄⁺

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$130M

Top sourceIsrael 39%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291815 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 291815, which covers 34 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IL 39%IsraelIN 14%IndiaDE 13%GermanyCN 10%ChinaIT 6%Italy

Brazil
Japan
Netherlands
Australia
Lithuania
United Kingdom
Norway
South Korea
Czech Republic
Lebanon
Ireland
Turkey
Estonia
Mexico
Switzerland

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

George S. Coyne Chemical

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Hydrite Chemical

Why It Matters

Sectors

WaterMetals & Mining

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 2 sectors as 2 functional roles.

•Chelating agent in Primary Metal ManufacturingProcessing—incorporation into article
•Cleaning agent in Utilities (100%)Use—non-incorporative activities

Chemical Identity

CAS3012-65-5

PubChem CID18171

DTXSIDDTXSID5020079

FormulaC6H14N2O7

Mol. Weight226.18 g/mol

SMILESC(C(=O)[O-])C(CC(=O)[O-])(C(=O)O)O.[NH4+].[NH4+]

Data Sources

EPA CompTox (DSSTox) · DTXSID5020079Retrieved 2026-04-06
PubChem · compound 18171Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Diammonium citrate (CAS 3012-65-5) https://chemicalindependence.com/chemical/3012-65-5/ EPA CompTox (DSSTox): DTXSID5020079. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID5020079 PubChem: 18171. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/18171 EPA Chemical Data Reporting: 3012-65-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 3012-65-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291815 for CAS 3012-65-5. Reporting year: 2024. https://usatrade.census.gov/