Treosulfan

Drug ingredient

CAS 299-75-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$78M

Top sourceChina 68%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290549 · basket

These shares come from HS customs code 290549, which covers 12 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 68%ChinaIT 16%ItalyFI 7%FinlandIN 4%IndiaDE 4%Germany

Japan
Canada
Switzerland
Malaysia
Netherlands
United Kingdom
Mexico
Taiwan
Singapore
Slovakia

1 FDA-registered drug labeler

Medexus Pharma, Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Grafapex

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS299-75-2

PubChem CID9882105

DTXSIDDTXSID0026173

FormulaC6H14O8S2

Mol. Weight278.3 g/mol

SMILESCS(=O)(=O)OCC(C(COS(=O)(=O)C)O)O

Data Sources

PubChem · compound 9882105Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Treosulfan (CAS 299-75-2) https://chemicalindependence.com/chemical/299-75-2/ PubChem: 9882105. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/9882105 FDA National Drug Code directory: CAS 299-75-2. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 290549 for CAS 299-75-2. Reporting year: 2024. https://usatrade.census.gov/