Potassium bicarbonate

Drug ingredient

CAS 298-14-6

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$19M

Top sourceSouth Korea 61%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.

Where It Comes From

Customs basis: HS 283640 · exact

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

Source Countries

Country of origin for US imports, from Census customs data (2024).

KR 61%South KoreaTW 17%TaiwanDE 8%GermanyCN 5%ChinaGB 3%United Kingdom

India
Japan
Israel
Switzerland

EPA-registered manufacturers (3)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Ecolab

Nachurs Alpine Solutions

Occidental Petroleum

Domestic parents -- activity not disclosed (2)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Avantor

Plant Products Holdings Usa

EPA-registered importers (6)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Master Plant-Prod · CA Canada

Kidde Residential & Commercial

Livingston International

Vitusa Products

Wilbur-Ellis Holdings Ii

Show all 6

Wintersun International

4 FDA-registered drug labelers

Bayer HealthCare LLC.

EMNAR PHARMA PRIVATE LIMITED

Nomax Inc.

Upsher-Smith Laboratories, Inc.

Why It Matters

Sectors

HealthAgricultureFoodEnergyMetals & MiningConsumer ProductsCore Chemicals

Downstream Uses

Appears in 10 drug and cosmetic product listings (FDA).

•Effer-K Cherry Berry
•Alka-Seltzer Gold
•Effer-K Unflavored
•Effer-K 20 mEq Unflavored
•Effer-K 10 mEq Cherry Vanilla
•Effer-K 20 mEq Orange Cream
•Effer-K Orange
•Effer-K Lemon Citrus

Show all 10

•Effer-K 10 mEq Unflavored
•KLOR-Con/EF

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 10 sectors as 8 functional roles.

•Soil amendments (fertilizers) in Agriculture, Forestry, Fishing and Hunting (35%)Use—non-incorporative activities
•Swelling agent in Petroleum Refineries (65%)Processing—incorporation into formulation, mixture, or reaction product
•pH regulating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
•Soil amendments (fertilizers) in Pesticide, Fertilizer, and Other Agricultural Chemical ManufacturingUse—non-incorporative activities
•Intermediate in All Other Basic Inorganic Chemical ManufacturingProcessing as a reactant
•Intermediate in Wholesale and Retail TradeProcessing—repackaging
•Fire extinguishing agent in Miscellaneous ManufacturingUse—non-incorporative activities
•Intermediate in All Other Chemical Product and Preparation ManufacturingProcessing as a reactant
•Surfactant (surface active agent) in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Cleaning agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Flavoring and nutrient in Food, beverage, and tobacco product manufacturing (60%)Processing—incorporation into article
•pH regulating agent in Pharmaceutical and Medicine Manufacturing (10%)Processing—incorporation into article

Chemical Identity

CAS298-14-6

PubChem CID516893

DTXSIDDTXSID0021177

FormulaCHKO3

Mol. Weight100.115 g/mol

SMILESC(=O)(O)[O-].[K+]

Data Sources

EPA CompTox (DSSTox) · DTXSID0021177Retrieved 2026-04-06
PubChem · compound 516893Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Potassium bicarbonate (CAS 298-14-6) https://chemicalindependence.com/chemical/298-14-6/ EPA CompTox (DSSTox): DTXSID0021177. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0021177 PubChem: 516893. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/516893 EPA Chemical Data Reporting: 298-14-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 298-14-6. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 283640 for CAS 298-14-6. Reporting year: 2024. https://usatrade.census.gov/