Guanfacine

Drug ingredient

CAS 29110-47-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$240M

Top sourceChina 37%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292529 · basket

These shares come from HS customs code 292529, which covers 64 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 37%ChinaDE 19%GermanyES 9%SpainIT 8%ItalyID 8%Indonesia

Switzerland
Canada
United Kingdom
Austria
Brazil
Israel
Australia
Hungary
Serbia
Denmark
Malaysia
Poland
Hong Kong
Ukraine
Singapore

6 FDA-registered drug labelers

American Health Packaging

Golden State Medical Supply, Inc.

Proficient Rx LP

REMEDYREPACK INC.

Unichem Pharmaceuticals (USA), Inc.

Upsher-Smith Laboratories, LLC

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Guanfacine Extended-Release
•Guanfacine Hydrochloride

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No Shortage

Shortage History

Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.

to be discontinued
Guanfacine Hydrochloride Tablet, Extended Release
Shortage listed since November 13, 2025

See all current drug shortages

Vendor Pricing

$245.00/gCombi-Blocks, Inc.

CountryUnited States

Pack$245.00 / 1 g

Purity95%

Vendors12 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

11 more vendors

Vendor	Country	$/g	Pack	Purity
Aaron Chemicals LLC	Hong Kong	$246.00	1 g	98%
Angene Chemical	China → Hong Kong	$283.00	1 g	98%
Ambeed, Inc.	United States	$436.00	250 mg	98%
AA BLOCKS	United States	$540.00	100 mg	98%
AstaTech (2 weeks)	United States	$684.00	1 g	95%
A2B Chem LLC	United States	$1720.00	250 mg	98%
MedChemExpress MCE	Sweden	$3690.50	100 mg	99.85%
Apexbio Technology LLC	United States	$4200.00	50 mg	99.98%
Angene International Limited	United States	$5380.00	100 mg	98%
TimTec, LLC	United States	$32000.00	10 mg	90%
Cayman Europe	Estonia	$756840.00	1 mg	95%

Chemical Identity

CAS29110-47-2

PubChem CID3519

DTXSIDDTXSID9046944

FormulaC9H9Cl2N3O

Mol. Weight246.09 g/mol

SMILESC1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl

Data Sources

PubChem · compound 3519Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA Drug ShortagesRetrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Guanfacine (CAS 29110-47-2) https://chemicalindependence.com/chemical/29110-47-2/ PubChem: 3519. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/3519 FDA National Drug Code directory: CAS 29110-47-2. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 29110-47-2. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 292529 for CAS 29110-47-2. Reporting year: 2024. https://usatrade.census.gov/