Netupitant

Drug ingredient

CAS 290297-26-6

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$7.6B

Top sourceIreland 61%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India

Israel
Bulgaria
Japan
Spain
Sweden
Canada
Taiwan
Finland
Portugal
Mexico
Belgium
Hungary
Austria
Brazil
Ukraine
Croatia
Malta
South Korea
South Africa
Denmark
Czech Republic
Malaysia
Argentina
Poland
Cameroon
Australia
Hong Kong
Slovakia
Latvia

3 FDA-registered drug labelers

Apicore Pharmaceuticals Private Limited

Helsinn Therapeutics (U.S.), Inc.

MSN Laboratories Private Limited

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Akynzeo

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$20.20/gAaron Chemicals LLC

CountryHong Kong

Pack$505.00 / 25 g

Purity99%

Vendors22 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

21 more vendors

Vendor	Country	$/g	Pack	Purity
Combi-Blocks, Inc.	United States	$21.60	25 g	95%
Angene Chemical	China → Hong Kong	$23.16	25 g	99%
BLD Pharmatech Ltd.	China	$24.80	25 g	99%
A2B Chem LLC	United States	$25.20	5 g	99%
AA BLOCKS	United States	$28.00	5 g	99%
BLD Pharmatech Co., Limited	United States	$35.40	5 g	99%
BLD Pharmatech GmbH	Germany	$35.40	5 g	99%
Ambeed, Inc.	United States	$35.40	5 g	99%
AK Scientific Specialized	United States	$66.00	1 g	95%
AK Scientific, Inc.	United States	$92.00	1 g	99%
Angene International Limited	United States	$177.00	1 g	99%
MedKoo Biosciences, Inc	United States	$930.00	5 g	98%
Molnova	China	$1594.00	500 mg	99%
TargetMol Chemicals	China → United States	$1772.00	500 mg	99.95%
TargetMol Chemicals EU	Austria	$2790.00	200 mg	99.95%
Apexbio Technology LLC	United States	$3890.00	100 mg	99.6%
Angene	China → Hong Kong	$4266.67	30 mg	99%
AstaTech, Inc	United States	$4580.00	100 mg	98%
MedChemExpress MCE	Sweden	$5747.50	100 mg	99.9%
Cayman Europe	Estonia	$8425.20	50 mg	98%
Axon Medchem	Netherlands	$12960.00	50 mg	99%

Chemical Identity

CAS290297-26-6

PubChem CID6451149

DTXSIDDTXSID50183271

FormulaC30H32F6N4O

Mol. Weight578.6 g/mol

SMILESCC1=CC=CC=C1C2=CC(=NC=C2N(C)C(=O)C(C)(C)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)N4CCN(CC4)C

Data Sources

PubChem · compound 6451149Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Netupitant (CAS 290297-26-6) https://chemicalindependence.com/chemical/290297-26-6/ PubChem: 6451149. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6451149 FDA National Drug Code directory: CAS 290297-26-6. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293359 for CAS 290297-26-6. Reporting year: 2024. https://usatrade.census.gov/