Pyrimidine

CAS 289-95-2

Companies reported imports and no US production of this chemical to EPA for 2023.

US productionZero

Import value, 2024$7.6B

Import volume22.9K lb

Import dependency100%

Top sourceIreland 61%

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Pyrimidine · US import value by year

2013: $4.4B · Peak 2024: $7.6B · 2025: $4.0B

Where It Comes From

Customs basis: HS 293359 · basket

EPA reports by year

2023: US production Zero · Imports 22.9K lb

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India

Israel
Bulgaria
Japan
Spain
Sweden
Canada
Taiwan
Finland
Portugal
Mexico
Belgium
Hungary
Austria
Brazil
Ukraine
Croatia
Malta
South Korea
South Africa
Denmark
Czech Republic
Malaysia
Argentina
Poland
Cameroon
Australia
Hong Kong
Slovakia
Latvia

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Sepro

Why It Matters

Sectors

Energy

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in Cyclic Crude and Intermediate Manufacturing (100%)Processing as a reactant

Vendor Pricing

$0.52/gAaron Chemicals LLC

CountryHong Kong

Pack$261.00 / 500 g

Purity98%

Vendors18 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

17 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.56	500 g	98%
Combi-Blocks, Inc.	United States	$0.72	500 g	98%
A2B Chem LLC	United States	$0.72	100 g	98%
AA BLOCKS	United States	$0.81	500 g	98%
AstaTech, Inc	United States	$0.82	100 g	98%
Chemscene	United States	$1.02	100 g	—
Ambeed, Inc.	United States	$1.08	25 g	98%
AK Scientific Specialized	United States	$2.40	500 g	97%
AK Scientific, Inc.	United States	$3.29	500 g	99%
MedChemExpress MCE	Sweden	$13.02	25 g	99.99%
TargetMol Chemicals	China → United States	$14.50	2 g	99.85%
Angene International Limited	United States	$18.20	5 g	99%
Sigma-Aldrich (Rush Stock)	Germany	$20.18	25 g	98%
Sigma-Aldrich	Germany	$20.18	25 g	98%
ALFA AESAR	Germany	$41.16	1 g	99%
Angene	China → Hong Kong	$4266.67	30 mg	98%
Molnova	China	$9800.00	5 mg	99%

Chemical Identity

CAS289-95-2

PubChem CIDNot recorded

DTXSIDDTXSID1051228

FormulaC4H4N2

Mol. Weight80.09 g/mol

SMILESC1=CN=CN=C1

Data Sources

EPA TSCA InventoryRetrieved 2026-04-29
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Pyrimidine (CAS 289-95-2) https://chemicalindependence.com/chemical/289-95-2/ EPA TSCA Inventory: CAS 289-95-2. Retrieved 2026-04-29. https://www.epa.gov/tsca-inventory EPA Chemical Data Reporting: 289-95-2. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 289-95-2. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293359 for CAS 289-95-2. Reporting year: 2024. https://usatrade.census.gov/