Calcium (S)-2-hydroxypropionate

CAS 28305-25-1

Propanoic acid, 2-hydroxy-, calcium salt (2:1), (2S)-

Molecular structure of 28305-25-1 — 1 Ca²⁺

US productionNot reported

Import value, 2024$78M

Top sourceNetherlands 33%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291811 · basket

These shares come from HS customs code 291811, which covers 35 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

NL 33%NetherlandsBE 14%BelgiumES 13%SpainCN 12%ChinaIT 9%Italy

Mexico
United Kingdom
Switzerland
Austria
South Korea
Sweden
Taiwan
Ukraine

Why It Matters

No EPA sector or FDA product records name a use for this chemical.

Vendor Pricing

$0.02/gAaron Chemicals LLC

CountryHong Kong

Pack$9.00 / 500 g

Purity98%

Vendors10 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

9 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.02	500 g	98%
A2B Chem LLC	United States	$0.11	500 g	98%
AA BLOCKS	United States	$0.14	500 g	98%
BLD Pharmatech Ltd.	China	$0.20	100 g	97%
Synthonix	United States	$0.52	500 g	95%
AstaTech, Inc	United States	$3.29	100 g	95%
Angene International Limited	United States	$5.27	100 g	98%
TargetMol Chemicals	China → United States	$56.00	1 g	98%
Angene	China → Hong Kong	$4266.67	30 mg	98%

Chemical Identity

CAS28305-25-1

PubChem CIDNot recorded

DTXSIDDTXSID80892243

FormulaC12H20CaO12

Mol. Weight396.359 g/mol

SMILES[Ca++].C[C@H](O)C([O-])=O.C[C@H](O)C([O-])=O.C[C@H](O)C([O-])=O.C[C@H](O)C([O-])=O

Data Sources

EPA TSCA InventoryRetrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Calcium (S)-2-hydroxypropionate (CAS 28305-25-1) https://chemicalindependence.com/chemical/28305-25-1/ EPA TSCA Inventory: CAS 28305-25-1. Retrieved 2026-10-04. https://www.epa.gov/tsca-inventory US Census international trade: HS 291811 for CAS 28305-25-1. Reporting year: 2024. https://usatrade.census.gov/