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Etidronic acid

Drug ingredient

CAS 2809-21-4

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

Molecular structure of 2809-21-4
US productionCBI
Import value, 2024$598M
Top sourceChina 89%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293149 · basket

EPA reports by year
2023
US production Confidential · Imports Confidential
2019
US production Confidential · Imports Confidential

These shares come from HS customs code 293149, which covers 114 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 89%ChinaIN 4%IndiaCA 3%CanadaDE 2%GermanyAR 1%Argentina
EPA-registered manufacturers (2)
Italmatch Chemicals Spa · IT Italy
Italmatch Usa
Domestic parents -- activity not disclosed (5)
Aurorium
Dystar
Nalco- An Ecolab
Polyventive
Seatex
EPA-registered importers (13)
Basf Se · DE Germany
Italmatch Chemicals Spa · IT Italy
Access Chemicals & Services
Allchem Industries Holding
Ambyth Chemical
Show all 13
Basf
Brenntag Northeast
Connect Chemicals Usa
Pvs Chemicals
Special Materials
Valudor Products
Wego Chemical Group
Zschimmer&Schwarz
1 FDA-registered drug labeler
Professional Complementary Health Formulas

Why It Matters

Sectors
HealthEnergyWaterElectronicsConstructionMetals & MiningTextilesConsumer ProductsPaper & PrintingCore Chemicals
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Spa/Pool Detox 6027
FDA Shortage Status
No FDA shortage records

Industrial Uses

Used in 15 sectors as 10 functional roles.

  • •Anti-scaling agent in All Other Chemical Product and Preparation Manufacturing (50%)Processing—incorporation into formulation, mixture, or reaction product
  • •Corrosion inhibitor in All Other Chemical Product and Preparation Manufacturing (50%)Processing—incorporation into formulation, mixture, or reaction product
  • •Stabilizing agent in All Other Basic Organic Chemical Manufacturing (20%)Processing as a reactant
  • •Stabilizing agent in Not Known or Reasonably Ascertainable (10%)Processing—repackaging
  • •Stabilizing agent in Paper Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Stabilizing agent in Oil and Gas Drilling, Extraction, and Support activities (10%)Processing—incorporation into formulation, mixture, or reaction product
  • •Stabilizing agent in Computer and Electronic Product Manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product
  • •Anti-stain agent in Other (0%)Processing—incorporation into formulation, mixture, or reaction product
  • •Anti-scaling agent in All Other Basic Organic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Anti-scaling agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
  • •Chelating agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (16%)Processing—incorporation into formulation, mixture, or reaction product
  • •Brightener in Wood Product Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
  • •Chelating agent in All Other Chemical Product and Preparation Manufacturing (62%)Processing—incorporation into formulation, mixture, or reaction product
  • •Chelating agent in Primary Metal Manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product
  • •Chelating agent in Textiles, apparel, and leather manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
  • •Chelating agent in All Other Basic Organic Chemical Manufacturing (10%)Use—non-incorporative activities
  • •Lubricating agent in Petroleum Lubricating Oil and Grease Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
  • •Anti-scaling agent in Oil and Gas Drilling, Extraction, and Support activities (45%)Processing—incorporation into formulation, mixture, or reaction product
  • •Dye in Textiles, apparel, and leather manufacturingProcessing—repackaging
  • •Anti-scaling agent in Miscellaneous Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Deflocculant in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Corrosion inhibitor in Utilities (100%)Use—non-incorporative activities
  • •Preservative in Asphalt Paving, Roofing, and Coating Materials ManufacturingProcessing—incorporation into formulation, mixture, or reaction product

Chemical Identity

CAS2809-21-4
PubChem CID3305
DTXSIDDTXSID6023028
FormulaC2H8O7P2
Mol. Weight206.03 g/mol
SMILESCC(O)(P(=O)(O)O)P(=O)(O)O

Data Sources

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Brief citations

Etidronic acid (CAS 2809-21-4) https://chemicalindependence.com/chemical/2809-21-4/ EPA CompTox (DSSTox): DTXSID6023028. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID6023028 PubChem: 3305. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/3305 EPA Chemical Data Reporting: 2809-21-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 2809-21-4. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293149 for CAS 2809-21-4. Reporting year: 2024. https://usatrade.census.gov/