1,4-Diazabicyclo[2.2.2]octane
CAS 280-57-9
U.S. production volumes are classified as confidential business information.
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 293359 · basket
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
- Israel
- Bulgaria
- Japan
- Spain
- Sweden
- Canada
- Taiwan
- Finland
- Portugal
- Mexico
- Belgium
- Hungary
- Austria
- Brazil
- Ukraine
- Croatia
- Malta
- South Korea
- South Africa
- Denmark
- Czech Republic
- Malaysia
- Argentina
- Poland
- Cameroon
- Australia
- Hong Kong
- Slovakia
- Latvia
Show all 6
Why It Matters
Industrial Uses
Used in 6 sectors as 4 functional roles.
- •Catalyst in All Other Basic Organic Chemical Manufacturing (100%)Processing—incorporation into article
- •Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Utilities (100%)Processing as a reactant
- •Catalyst in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Catalyst in Transportation Equipment Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Catalyst in ConstructionProcessing—incorporation into formulation, mixture, or reaction product
- •Absorbent in Oil and Gas Drilling, Extraction, and Support activities (100%)Processing as a reactant
Vendor Pricing
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
27 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| Angene Chemical | China → Hong Kong | $0.03 | 500 g | 99% |
| A2B Chem LLC | United States | $0.04 | 1 kg | 98% |
| AA BLOCKS | United States | $0.04 | 500 g | 98% |
| Chemscene | United States | $0.05 | 1 kg | — |
| Fluorochem UK | United Kingdom | $0.07 | 1 kg | 99% |
| Apollo Scientific US | United Kingdom | $0.07 | 1 kg | 95% |
| Fluorochem EU | Germany | $0.07 | 1 kg | 99% |
| Angene International Limited | United States | $0.09 | 500 g | 98% |
| Ambeed, Inc. | United States | $0.18 | 500 g | 98% |
| AK Scientific Specialized | United States | $0.20 | 1 kg | 98% |
| Synthonix | United States | $0.22 | 500 g | 95% |
| AK Scientific, Inc. | United States | $0.25 | 1 kg | 99.5% |
| Combi-Blocks, Inc. | United States | $0.25 | 1 kg | 98% |
| MedChemExpress MCE | Sweden | $0.31 | 100 g | 99.99% |
| Sigma-Aldrich (Rush Stock) | Germany | $0.41 | 2 kg | 99% |
| Sigma-Aldrich | Germany | $0.41 | 2 kg | 99% |
| AstaTech, Inc | United States | $0.67 | 100 g | 95% |
| Aldlab | United States | $0.72 | 25 g | 95% |
| Labotest KG | Germany | $217.80 | 5000 mg | 90% |
| Key Organics Ltd. | United Kingdom | $1960.00 | 100 mg | 95% |
| Otava, Ltd. | Ukraine | $2280.00 | 50 mg | 95% |
| Otava, Ltd. (2 weeks) | Ukraine | $2724.00 | 50 mg | 95% |
| Princeton BioMolecular Research (SC) | United States | $2900.00 | 100 mg | 90% |
| Vitas M Chemical Limited | Hong Kong | $3170.00 | 100 mg | 90% |
| Angene | China → Hong Kong | $4266.67 | 30 mg | 99% |
| Asinex | Netherlands | $6461.40 | 100 mg | 90% |
| TimTec, LLC (back-ordered) | United States | $32000.00 | 15 mg | 94% |
Chemical Identity
Data Sources
- EPA CompTox (DSSTox) · DTXSID0022016Retrieved 2026-04-06
- PubChem · compound 9237Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
1,4-Diazabicyclo[2.2.2]octane (CAS 280-57-9) https://chemicalindependence.com/chemical/280-57-9/ EPA CompTox (DSSTox): DTXSID0022016. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0022016 PubChem: 9237. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/9237 EPA Chemical Data Reporting: 280-57-9. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 280-57-9. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293359 for CAS 280-57-9. Reporting year: 2024. https://usatrade.census.gov/