2-Propenoic acid, 2-cyano-, 2-methoxyethyl ester

CAS 27816-23-5

Used in 2 industrial sectors tracked by the EPA.

US production5.7K lb

Import value, 2024$281M

Import volume16.7K lb

Import dependency74%

Top sourceChina 31%

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292690 · basket

EPA reports by year

2023: US production 5.7K lb · Imports 16.7K lb

These shares come from HS customs code 292690, which covers 191 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 31%ChinaIT 15%ItalyGB 14%United KingdomIN 11%IndiaJP 8%Japan

South Korea
Spain
Ireland
Ukraine
Malaysia
Brazil
Hong Kong
Latvia
Australia

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Henkel

Why It Matters

Sectors

ElectronicsMetals & Mining

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 3 sectors as 1 functional role.

•Monomers in Machinery Manufacturing (40%)Processing—incorporation into formulation, mixture, or reaction product
•Monomers in Computer and Electronic Product Manufacturing (41%)Processing—incorporation into formulation, mixture, or reaction product
•Monomers in Electrical Equipment, Appliance, and Component Manufacturing (20%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.56/gCombi-Blocks, Inc.

CountryUnited States

Pack$280.00 / 500 g

Purity98%

Vendors11 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

10 more vendors

Vendor	Country	$/g	Pack	Purity
Aaron Chemicals LLC	Hong Kong	$0.66	500 g	98%
BLD Pharmatech Ltd.	China	$0.66	500 g	98%
Angene Chemical	China → Hong Kong	$0.70	500 g	98%
A2B Chem LLC	United States	$0.71	500 g	98%
AA BLOCKS	United States	$0.75	500 g	98%
BLD Pharmatech Co., Limited	United States	$0.80	100 g	98%
Ambeed, Inc.	United States	$0.80	100 g	98%
AstaTech (2 weeks)	United States	$0.90	500 g	95%
BLD Pharmatech GmbH	Germany	$1.00	25 g	98%
Angene	China → Hong Kong	$4266.67	30 mg	98%

Chemical Identity

CAS27816-23-5

PubChem CIDNot recorded

DTXSIDDTXSID0067341

FormulaC7H9NO3

Mol. Weight155.153 g/mol

SMILESCOCCOC(=O)C(=C)C#N

Data Sources

EPA TSCA InventoryRetrieved 2026-04-29
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

2-Propenoic acid, 2-cyano-, 2-methoxyethyl ester (CAS 27816-23-5) https://chemicalindependence.com/chemical/27816-23-5/ EPA TSCA Inventory: CAS 27816-23-5. Retrieved 2026-04-29. https://www.epa.gov/tsca-inventory EPA Chemical Data Reporting: 27816-23-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 27816-23-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292690 for CAS 27816-23-5. Reporting year: 2024. https://usatrade.census.gov/