1,3,4-Thiadiazole, 2-(methylsulfonyl)-5-(trifluoromethyl)-

CAS 27603-25-4

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Top sourceNo public record

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.

Where It Comes From

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

EPA-registered manufacturers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Bayer Ag · DE Germany

Bayer Us Holding

Why It Matters

Sectors

Agriculture

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing as a reactant

Vendor Pricing

$129.80/gAstaTech (2 weeks)

CountryUnited States

Pack$649.00 / 5 g

Purity95%

Vendors10 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

9 more vendors

Vendor	Country	$/g	Pack	Purity
BLD Pharmatech Ltd.	China	$145.00	1 g	95%
Ambeed, Inc.	United States	$145.00	1 g	95%
Combi-Blocks, Inc.	United States	$152.00	5 g	95%
BLD Pharmatech Co., Limited	United States	$230.00	1 g	95%
Angene Chemical	China → Hong Kong	$294.00	1 g	95%
A2B Chem LLC	United States	$316.00	250 mg	95%
Aaron Chemicals LLC	Hong Kong	$320.00	1 g	95%
AA BLOCKS	United States	$348.00	250 mg	95%
Key Organics Ltd.	United Kingdom	$1180.00	250 mg	95%

Chemical Identity

CAS27603-25-4

PubChem CID5062481

DTXSIDDTXSID70865385

FormulaC4H3F3N2O2S2

Mol. Weight232.2 g/mol

SMILESCS(=O)(=O)C1=NN=C(S1)C(F)(F)F

Data Sources

EPA CompTox (DSSTox) · DTXSID70865385Retrieved 2026-04-06
PubChem · compound 5062481Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04

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Brief citations

1,3,4-Thiadiazole, 2-(methylsulfonyl)-5-(trifluoromethyl)- (CAS 27603-25-4) https://chemicalindependence.com/chemical/27603-25-4/ EPA CompTox (DSSTox): DTXSID70865385. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID70865385 PubChem: 5062481. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/5062481 EPA Chemical Data Reporting: 27603-25-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 27603-25-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting