Ensulizole

Drug ingredient

CAS 27503-81-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 27503-81-7
US productionNot reported
Import value, 2024$1.4B
Top sourceIreland 33%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293399 · basket

These shares come from HS customs code 293399, which covers 518 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 33%IrelandCN 26%ChinaIN 11%IndiaDE 9%GermanyIT 4%Italy
36 FDA-registered drug labelers
Access Business Group LLC
AHAVA - Dead Sea Laboratories Ltd
Amway Corp
Beiersdorf Inc
Biocosmetica Exel Argentina SRL
Chemspec Chemicals PVT LTD
CLINIQUE LABORATORIES LLC
CONOPCO Inc. d/b/a Unilever
Cosmocos Co., Ltd
DSM Nutritional Products LLC
ESTEE LAUDER INC
Exelencia importers Corp.
fmg Co.Ltd
Foshan Sugar Max Cosmetics CO.,Ltd
Guangzhou Meixi Biotechnology Co., Ltd.
Hangzhou Jingshen Trading Co., Ltd.
IT COSMETICS, LLC
L'Oreal USA Products Inc
LG H&H Co., Ltd.
Longway Technology(Guangzhou) Co., Ltd.
Manyo Factory Corp.
NATURECELL CO., LTD.
NOXELL CORPORATION
Parfums Christian Dior
Pella Pharmaceuticals Co. Ltd
SHISEIDO AMERICAS CORPORATION
SICOS ET CIE
SIMPLI SKIN MD LLC
Sled Distribution, LLC
STRYX MEN, INC.
Susonity Production GmbH
Symrise AG
Symrise Inc.
Tecnoglobal, PH7 S.A. DE C.V.
TOM FORD BEAUTY DIST
Yidu Huayang Chemical Co., Ltd.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 69 drug and cosmetic product listings (FDA).

  • •Phofay Matte Sunscreen Liquid Foundation SPF 30 2
  • •Phofay Matte Sunscreen Liquid Foundation SPF 30 3
  • •Manyo Air Light Moisturizing Sunscreen SPF 50
  • •LOreal Paris Skin Paradise Water Infused Tinted Moisturizer Broad Spectrum SPF 19 Sunscreen
  • •Capture Totale C.E.L.L. Energy Super Potent Serum Foundation Broad Spectrum SPF 20 1N
  • •Thefaceshop Cushion CC SPF 50 Apricot Beige Oil-Free
  • •Koneuk Sunscreen SPF50
  • •Eucerin Daily Protection Face
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.09/gA2B Chem LLC
CountryUnited States
Pack$85.00 / 1 kg
Purity98%
Vendors16 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS27503-81-7
PubChem CID33919
DTXSIDDTXSID3038852
FormulaC13H10N2O3S
Mol. Weight274.3 g/mol
SMILESC1=CC=C(C=C1)C2=NC3=C(N2)C=C(C=C3)S(=O)(=O)O

Data Sources

Brief citations

Ensulizole (CAS 27503-81-7) https://chemicalindependence.com/chemical/27503-81-7/ PubChem: 33919. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/33919 EPA TSCA Inventory: CAS 27503-81-7. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293399 for CAS 27503-81-7. Reporting year: 2024. https://usatrade.census.gov/