2-Methyl-3(2H)-isothiazolone

Drug ingredient

CAS 2682-20-4

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

Molecular structure of 2682-20-4
US productionCBI
Import value, 2024$447M
Top sourceChina 31%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293410 · basket

EPA reports by year
2023
US production Confidential · Imports Confidential
2019
US production Confidential · Imports Confidential

These shares come from HS customs code 293410, which covers 83 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 31%ChinaDE 25%GermanyMX 19%MexicoJP 13%JapanIN 5%India
EPA-registered manufacturers (2)
Indorama Netherlands Bv · NL Netherlands
Indorama Ventures Usa Holdings
EPA-registered importers (3)
Basf Se · DE Germany
Basf
The Sherwin Williams

Why It Matters

Sectors
HealthAgricultureEnergyTransportationConstructionMetals & MiningPlastics & RubberConsumer ProductsPaints & CoatingsCore Chemicals
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Anubis Barcelona Regul Oil
FDA Shortage Status
No FDA shortage records

Industrial Uses

Used in 11 sectors as 7 functional roles.

  • •Surfactant (surface active agent) in Paint and Coating Manufacturing (100%)Processing as a reactant
  • •Surfactant (surface active agent) in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
  • •Preservative in Transportation Equipment Manufacturing (0%)Processing—incorporation into article
  • •Preservative in Wood Product Manufacturing (0%)Processing—incorporation into article
  • •Preservative in Not Known or Reasonably AscertainableProcessing—incorporation into formulation, mixture, or reaction product
  • •Preservative in Paint and Coating ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Preservative in Plastics Material and Resin Manufacturing (4%)Processing—incorporation into formulation, mixture, or reaction product
  • •Preservative in Miscellaneous Manufacturing (0%)Processing—incorporation into article
  • •Preservative in Furniture and Related Product Manufacturing (0%)Processing—incorporation into article
  • •Emulsifier in OtherProcessing as a reactant
  • •Lubricating agent in Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing)Use—non-incorporative activities
  • •Corrosion inhibitor in Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing)Use—non-incorporative activities
  • •Surfactant (surface active agent) in OtherProcessing—incorporation into formulation, mixture, or reaction product
  • •Brightener in Soap, Cleaning Compound, and Toilet Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Monomers in Paint and Coating ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Preservative in OtherProcessing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.58/gCombi-Blocks, Inc.
CountryUnited States
Pack$290.00 / 500 g
Purity98%
Vendors17 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS2682-20-4
PubChem CID39800
DTXSIDDTXSID2034259
FormulaC4H5NOS
Mol. Weight115.16 g/mol
SMILESCN1C(=O)C=CS1

Data Sources

Brief citations

2-Methyl-3(2H)-isothiazolone (CAS 2682-20-4) https://chemicalindependence.com/chemical/2682-20-4/ EPA CompTox (DSSTox): DTXSID2034259. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID2034259 PubChem: 39800. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/39800 EPA Chemical Data Reporting: 2682-20-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 2682-20-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293410 for CAS 2682-20-4. Reporting year: 2024. https://usatrade.census.gov/