Naproxen sodium
Drug ingredientCAS 26159-34-2
This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.
US productionNot reported
Import value, 2024$370M
Top sourceIndia 45%
This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.
Why supply is unknownProduction is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 291899 · basket
These shares come from HS customs code 291899, which covers 139 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
Source Countries
Country of origin for US imports, from Census customs data (2024).
IN 45%IndiaCN 35%ChinaGB 7%United KingdomCO 3%ColombiaCH 3%Switzerland
- Austria
- Hungary
- South Korea
- Taiwan
- Czech Republic
- Mexico
- Spain
- Ukraine
- Estonia
- Australia
- Israel
- Singapore
- Slovakia
- Russia
134 FDA-registered drug labelers
A-S Medication Solutions
AAA Pharmaceutical, Inc.
AAFES/Your Military Exchanges
Acme United Corporation
Advanced Rx of Tennessee, LLC
Albertsons Companies
Allegiant Health
Almatica Pharma LLC
Alvogen Inc.
Amazon.com Services LLC
American Sales Company
AMERIFOODS TRADING COMPANY
AMERISOURCE BERGEN
AmerisourceBergen (Good Neighbor Pharmacy) 46122
Amneal Pharmaceuticals NY LLC
Amneal Pharmaceuticals of New York LLC
Army & Air Force Exchange Service
Asclemed USA, Inc.
Athlete's Needs Inc
Aurobindo Pharma Limited
Aurohealth LLC
Bayer HealthCare LLC
Belmora LLC
BETTER LIVING BRANDS LLC.
Bi-Mart
Bionpharma Inc.
BJWC
Bryant Ranch Prepack
Camber Consumer Care Inc
Cardinal Health 110, LLC. dba Leader
Care One (American Sales Company)
Care One (Retail Business Services, LLC.)
Catalent Argentina S.A.I.y C.
Chain Drug Marketing Association
CHAIN DRUG MARKETING ASSOCIATION INC.
Cintas Corporation
Command Brands, LLC
Costco Wholesale Company
Currax Pharmaceuticals LLC
Currax Pharmaceuticals LLC dba Cypress, Hawthorn, Macoven
CVS
CVS Pharmacy
CVS PHARMACY, INC
CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED
Direct Rx
DISCOUNT DRUG MART
DISCOUNT DRUG MART, INC.
Divi's Laboratories Limited
Dolgencorp Inc
Dolgencorp, Inc. (DOLLAR GENERAL & REXALL)
Dr Reddy's Laboratories Inc
Dr. Reddy's Laboratories Limited
EQUATE (Wal-Mart Stores, Inc.) (see also WAL-MART INC)
Family Dollar Services Inc
Farmacias De Similares TX LLC
FSA STORE INC.
Geri-Care Pharmaceutical Corp
Glenmark Pharmaceuticals Inc., USA
Gobrands, Inc
GRANDALL DISTRIBUTING, LLC
Granules India Limited
Granules India Ltd
Granules USA, Inc.
Grocery Outlet
H E B
Harris Teeter
HealthLife of USA LLC
Hetero Labs Limited
Humanwell PuraCap Pharmaceuticals (Wuhan) Co., Ltd
HYVEE INC
Kenvue Brands LLC
KROGER COMPANY
L. Perrigo Company
L.N.K. International, Inc.
LETCO MEDICAL, LLC
Lidl US LLC
Lil' Drug Store Products, Inc
Live Betr LLC
Marc Glassman, Inc.
MARKSANS PHARMA LIMITED
Medline Industries, LP
MEIJER DISTRIBUTION INC
Navajo Manufacturing Company Inc
New World Imports, Inc.
NorthStar RxLLC
NuCare Pharmaceuticals,Inc.
OPMX LLC
P & L Development, LLC
Padagis Israel Pharmaceuticals Ltd
Patheon Softgels Inc
PD-Rx Pharmaceuticals, Inc.
Pharmadel LLC
PHOENIX RX LLC
Preferred Pharmaceuticals Inc.
Premier Value Alliance LLC
Productos Zapotol Corp.
Proficient Rx LP
Publix Super Markets Inc
PuraCap Pharmaceutical LLC
Quality Care Products, LLC
R J General Corporation
Rite Aid Corporation
Rugby Laboratories
SA3, LLC
SAFEWAY
Safeway, Inc
SAM'S WEST INC
ScieGen Pharmaceuticals, Inc.
Select Consumer Group
Spectrum Laboratory Products, Inc.
SPIRIT PHARMACEUTICALS,LLC
Sportpharm, Inc. dba Sportpharm
ST. MARY'S MEDICAL PARK PHARMACY
Strategic Sourcing Services LLC
Sun Pharmaceutical Industries, Inc.
SUPERVALU INC
TARGET CORPORATION
Teva Pharmaceuticals, Inc.
TIME CAP LABORATORIES, INC
TOP CARE (Topco Associates LLC)
Topco Associates LLC
Unifirst First Aid Corporation
United Natural Foods, Inc. dba UNFI
Upsher-Smith Laboratories, LLC
VALU MERCHANDISERS COMPANY
VESPYR BRANDS, INC.
Wal-Mart Stores, Inc.
WALGREEN COMPANY
WALGREENS
Walmart
WALMART INC.
WinCo Foods, LLC
Zapotol Products Corp
Zhejiang Charioteer Pharmaceutical Co., Ltd.
Why It Matters
Sectors
Health
Downstream Uses
Appears in 90 drug and cosmetic product listings (FDA).
- •Naproxen Sodium
- •Aleve Caplets
- •Flanax
- •Flanax Menstrual Pain Reliever
- •Good Sense Naproxen Sodium
- •Care One Naproxen Sodium
- •Sumatriptan and Naproxen Sodium
- •Careall Naproxen
Show all 90
- •Naproxen
- •all day relief
- •Aleve Headache Pain
- •All Day Pain Relief
- •kirkland signature naproxen sodium
- •Naproxen Caplets All day relief for pain
- •Proxen NP 660
- •Naproxen Sodium Diphenhydramine HCl
- •Rugby All Day Relief
- •basic care naproxen sodium pm
- •Amazon Basic CARE Naproxen Sodium
- •Pain Relief
- •signature care naproxen sodium
- •Topcare All Day Pain Relief
- •Topcare Sinus and Cold D
- •Sumatriptan Succinate and Naproxen Sodium
- •Belmora Flanax
- •Medique Mediproxen
- •Naproxen Sodium and Pseudoephedrine Hydrochloride Sinus and Cold
- •Aleve Easy Open Arthritis
- •All Day Sinus and Cold D
- •Naproxen Caplets
- •Aleve
- •Naproxen Sodium PM
- •Naproxen Sodium AND Pseudoephedrine Hydrochloride COLD AND Sinus
- •Naproxen Sodium and Diphenhydramine HCL
- •Flanax Pain Reliever/Fever reducer
- •Sinus and Cold D
- •Naproxen Sodium Caplets
- •Naproxen Sodium Headache Pain Caplets
- •Naproxen Headache Pain
- •Careall Naproxen Sodium
- •Aleve Gelcaps
- •Naproxen Sodium 220mg
- •up and up naproxen sodium pm
- •AnaDent
- •equaline naproxen sodium
- •Naproxen Sodium (Nsaid) Fever Reducer/ Pain Reliever
- •DG Health Naproxen Sodium
- •dg health naproxen sodium pm
- •Aleve Back and Muscle Pain
- •Aleve Caplets Easy Open Arthritis
- •Aleve-D Sinus and Cold
- •up and up naproxen sodium
- •Back and Muscle Pain
- •Naproxen Sodium Headache Pain
- •Naproxen Sodium Back and Muscle Pain
- •exchange select naproxen sodium
- •Rapidol Naproxen
- •Naproxen Sodium and Pseudoephedrine Hydrochloride Sinus and Headache
- •Aleve PM
- •Aleve Caplets - Easy Open Arthritis Cap
- •Aleve Easy Open Arthritis Cap
- •Aleve, Travel Basix
- •Leader All Day Pain Relief
- •Basic Care Naproxen Sodium
- •Aleve liquid gels
- •24/7 Life by 7-Eleven Naproxen Sodium
- •Lil Drug Store Pain Relief All Day
- •All Day Back and Muscle Pain Relief
- •Bayer Aleve
- •topcare all night pain relief pm
- •topcare back and muscle pain
- •equaline naproxen sodium pm
- •Treximet
- •Naproxen Sodium Back and Muscle Pain Caplets
- •Sudafed Sinus 12 Hour Pressure plus Pain
- •Berkley and Jensen Naproxen Sodium
- •Dr Simi All Day Pain Relief
- •Naprelan
- •careone naproxen sodium pm
- •First Aid Direct All Day Pain Relief
- •Calmadol PAIN Reliever
- •foster and thrive all day pain relief
- •betr headache pain relief
- •Ana-Dent PAIN Relief
- •Medique at Home Mediproxen
- •Leader All Day Sinus and Cold D
- •Naproxen Sodium Diphenhydramine Hydrochloride
- •Naproxen Back and Muscle Pain
- •Aleve Caplets Soft Grip Arthritis
- •Aleve-D Sinus and Headache
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Chemical Identity
CAS26159-34-2
PubChem CID23681059
DTXSIDDTXSID7045576
FormulaC14H13NaO3
Mol. Weight252.24 g/mol
SMILESCC(C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)[O-].[Na+]
Data Sources
- PubChem · compound 23681059Retrieved 2026-04-07
- FDA National Drug Code directoryRetrieved 2026-04-25
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Naproxen sodium (CAS 26159-34-2) https://chemicalindependence.com/chemical/26159-34-2/ PubChem: 23681059. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/23681059 FDA National Drug Code directory: CAS 26159-34-2. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291899 for CAS 26159-34-2. Reporting year: 2024. https://usatrade.census.gov/