Methanesulfonamide, N-[2-[(4-amino-3-methylphenyl)ethylamino]ethyl]-, sulfate (2:3)

CAS 25646-71-3

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$2.0B

Top sourceIreland 63%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland

Portugal
Spain
Italy
Austria
Israel
Hungary
Canada
South Korea
Netherlands
Finland
Poland
Indonesia
Ukraine
Mexico
South Africa
Croatia
Greece
Taiwan
Hong Kong

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Fujifilm Holdings America

Why It Matters

Sectors

Consumer Products

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 1 sector as 2 functional roles.

•Oxidizing/reducing agents in Photographic Film, Paper, Plate, and Chemical Manufacturing (80%)Processing as a reactant
•Photosensitive chemicals in Photographic Film, Paper, Plate, and Chemical Manufacturing (100%)Use—non-incorporative activities

Vendor Pricing

$0.62/gAaron Chemicals LLC

CountryHong Kong

Pack$309.00 / 500 g

Purity95%

Vendors10 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

9 more vendors

Vendor	Country	$/g	Pack	Purity
Combi-Blocks, Inc.	United States	$0.69	500 g	95%
Angene Chemical	China → Hong Kong	$0.71	500 g	95%
A2B Chem LLC	United States	$0.74	500 g	95%
AA BLOCKS	United States	$0.78	500 g	95%
Ambeed, Inc.	United States	$0.95	100 g	95%
AstaTech (2 weeks)	United States	$2.60	25 g	95%
Angene International Limited	United States	$4.80	25 g	95%
Key Organics Ltd.	United Kingdom	$2080.00	50 mg	95%
Angene	China → Hong Kong	$4266.67	30 mg	95%

Chemical Identity

CAS25646-71-3

PubChem CID91578

DTXSIDDTXSID2027882

FormulaC24H48N6O16S5

Mol. Weight837 g/mol

SMILESCCN(CCNS(=O)(=O)C)C1=CC(=C(C=C1)N)C.CCN(CCNS(=O)(=O)C)C1=CC(=C(C=C1)N)C.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O

Data Sources

EPA CompTox (DSSTox) · DTXSID2027882Retrieved 2026-04-06
PubChem · compound 91578Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Methanesulfonamide, N-[2-[(4-amino-3-methylphenyl)ethylamino]ethyl]-, sulfate (2:3) (CAS 25646-71-3) https://chemicalindependence.com/chemical/25646-71-3/ EPA CompTox (DSSTox): DTXSID2027882. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID2027882 PubChem: 91578. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/91578 EPA Chemical Data Reporting: 25646-71-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 25646-71-3. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293590 for CAS 25646-71-3. Reporting year: 2024. https://usatrade.census.gov/