Tripropylene glycol monomethyl ether

CAS 25498-49-1

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$3M

Top sourceItaly 31%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290944 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 290944, which covers 13 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IT 31%ItalyCN 18%ChinaDE 12%GermanyJP 11%JapanTW 7%Taiwan

Spain
Switzerland
Austria

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Ineos Oxide

Domestic parents -- activity not disclosed (3)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Daxx

International Flavors And Fragrances

Reckitt Benckiser

EPA-registered importers (15)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Basf Se · DE Germany

Kowa · JP Japan

Reckitt Benckiser Group · GB United Kingdom

Allchem Industries Holding

Ambyth Chemical

Show all 15

Basf

Catalynt Solutions

Dow Chemical

Givaudan Fragrances

Greenchem Industries

Kowa Holdings America

Newell Brands

P&G

Target

Why It Matters

Sectors

EnergyTransportationMetals & MiningConsumer ProductsPaints & CoatingsCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 10 sectors as 5 functional roles.

•Solvent in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Solvent in Not Known or Reasonably Ascertainable (100%)Processing—incorporation into article
•Heat transferring agent in All Other Basic Organic Chemical Manufacturing (45%)Processing—incorporation into formulation, mixture, or reaction product
•Sealant (barrier) in All Other Basic Organic Chemical Manufacturing (45%)Processing—incorporation into formulation, mixture, or reaction product
•Fragrance in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (47%)Processing—incorporation into formulation, mixture, or reaction product
•Fragrance in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Solvent in All Other Basic Organic Chemical Manufacturing (10%)Use—non-incorporative activities
•Solvent in Oil and Gas Drilling, Extraction, and Support activities (3%)Processing—incorporation into formulation, mixture, or reaction product
•Intermediate in All Other Basic Organic Chemical Manufacturing (10%)Processing as a reactant
•Solvent in Transportation Equipment ManufacturingProcessing—incorporation into article
•Solvent in OtherProcessing—incorporation into formulation, mixture, or reaction product
•Solvent in All other Petroleum and Coal Products Manufacturing (2%)Processing—incorporation into formulation, mixture, or reaction product
•Solvent in Wholesale and Retail Trade (98%)Processing—repackaging

Chemical Identity

CAS25498-49-1

PubChem CIDNot recorded

DTXSIDDTXSID2029329

FormulaNot recorded

Mol. WeightNot recorded

SMILESNot recorded

Data Sources

EPA CompTox (DSSTox) · DTXSID2029329Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Tripropylene glycol monomethyl ether (CAS 25498-49-1) https://chemicalindependence.com/chemical/25498-49-1/ EPA CompTox (DSSTox): DTXSID2029329. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID2029329 EPA Chemical Data Reporting: 25498-49-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 25498-49-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290944 for CAS 25498-49-1. Reporting year: 2024. https://usatrade.census.gov/