Polypropylene glycol

CAS 25322-69-4

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$524M

Top sourceSouth Korea 27%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 390729 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 390729, which covers 46 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

KR 27%South KoreaDE 13%GermanyCN 11%ChinaJP 9%JapanCH 8%Switzerland

Brazil
Sweden
Argentina
India
Austria
Saudi Arabia
Poland
United Arab Emirates
Ireland
Latvia
Czech Republic
Bulgaria
Norway
Hungary
Denmark
Finland
Australia
Indonesia
Slovakia
Lithuania
Israel
Georgia
Costa Rica
Luxembourg
Romania
Philippines
Greece

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Macdermid

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Schlumberger

EPA-registered importers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Pvs Chemicals

Soyventis North America

Why It Matters

Sectors

EnergyCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 2 sectors as 5 functional roles.

•Plating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
•Chelating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
•Etching agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
•Hydraulic fluids in Oil and Gas Drilling, Extraction, and Support activities (0%)Processing—incorporation into formulation, mixture, or reaction product
•Waterproofing agent in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Chemical Identity

CAS25322-69-4

PubChem CIDNot recorded

DTXSIDDTXSID9027863

FormulaNot recorded

Mol. WeightNot recorded

SMILESNot recorded

Data Sources

EPA CompTox (DSSTox) · DTXSID9027863Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Polypropylene glycol (CAS 25322-69-4) https://chemicalindependence.com/chemical/25322-69-4/ EPA CompTox (DSSTox): DTXSID9027863. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID9027863 EPA Chemical Data Reporting: 25322-69-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 25322-69-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 390729 for CAS 25322-69-4. Reporting year: 2024. https://usatrade.census.gov/