Clobetasone butyrate

Drug ingredient

CAS 25122-57-0

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$1.1B

Top sourceSingapore 82%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293722 · basket

These shares come from HS customs code 293722, which covers 36 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

SG 82%SingaporeGB 15%United KingdomIT 2%Italy

India
Portugal
China
Mexico
Spain
Malaysia
Canada
Israel
Jordan
Belgium

1 FDA-registered drug labeler

SYMBIOTICA SPECIALITY INGREDIENTS SDN.BHD

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$79.60/gA2B Chem LLC

CountryUnited States

Pack$398.00 / 5 g

Purity98%

Vendors6 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

5 more vendors

Vendor	Country	$/g	Pack	Purity
AA BLOCKS	United States	$84.40	5 g	98%
Angene Chemical	China → Hong Kong	$167.00	1 g	95%
Labotest KG	Germany	$453.00	1000 mg	90%
Aaron Chemicals LLC	Hong Kong	$535.00	1 g	98%
Angene International Limited	United States	$632.00	1 g	98%

Chemical Identity

CAS25122-57-0

PubChem CID71386

DTXSIDDTXSID3046823

FormulaC26H32ClFO5

Mol. Weight479 g/mol

SMILESCCCC(=O)OC1(C(CC2C1(CC(=O)C3(C2CCC4=CC(=O)C=CC43C)F)C)C)C(=O)CCl

Data Sources

PubChem · compound 71386Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Clobetasone butyrate (CAS 25122-57-0) https://chemicalindependence.com/chemical/25122-57-0/ PubChem: 71386. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/71386 FDA National Drug Code directory: CAS 25122-57-0. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293722 for CAS 25122-57-0. Reporting year: 2024. https://usatrade.census.gov/