2-[(p-Aminophenyl)sulfonyl]ethyl hydrogen sulfate

CAS 2494-89-5

EPA’s 2023 records show zero U.S. production of this chemical.

US productionZero

Import value, 2024$760M

Import volumeCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Top sourceChina 33%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293090 · basket

EPA reports by year

2023: US production Zero · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 293090, which covers 418 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 33%ChinaES 14%SpainCH 9%SwitzerlandIT 7%ItalyIN 7%India

Israel
Croatia
Ukraine
Slovakia
United Arab Emirates
Ireland
Poland
Lithuania
Brazil
Singapore
Australia
Armenia
Hong Kong
Vietnam
Czech Republic
Hungary
Greece
Russia

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Cabot

Why It Matters

Sectors

Paper & Printing

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in Printing Ink Manufacturing (100%)Processing as a reactant

Vendor Pricing

$0.38/gCombi-Blocks, Inc.

CountryUnited States

Pack$380.00 / 1 kg

Purity95%

Vendors15 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

14 more vendors

Vendor	Country	$/g	Pack	Purity
A2B Chem LLC	United States	$0.41	1 kg	97%
AA BLOCKS	United States	$0.43	1 kg	97%
Aaron Chemicals LLC	Hong Kong	$0.43	500 g	97%
Angene Chemical	China → Hong Kong	$0.46	500 g	97%
Chemscene	United States	$0.67	100 g	—
Ambeed, Inc.	United States	$0.70	100 g	97%
AK Scientific Specialized	United States	$1.08	100 g	95%
AstaTech, Inc	United States	$1.32	25 g	92%
Fluorochem EU	Germany	$1.36	25 g	95%
AK Scientific, Inc.	United States	$1.52	100 g	98%
Angene International Limited	United States	$2.01	100 g	97%
Angene	China → Hong Kong	$4266.67	30 mg	97%
Princeton BioMolecular Research (SC)	United States	$8000.00	15 mg	90%
Vitas M Chemical Limited	Hong Kong	$9000.00	10 mg	90%

Chemical Identity

CAS2494-89-5

PubChem CID75615

DTXSIDDTXSID0027484

FormulaC8H11NO6S2

Mol. Weight281.3 g/mol

SMILESC1=CC(=CC=C1N)S(=O)(=O)CCOS(=O)(=O)O

Data Sources

EPA CompTox (DSSTox) · DTXSID0027484Retrieved 2026-04-06
PubChem · compound 75615Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

2-[(p-Aminophenyl)sulfonyl]ethyl hydrogen sulfate (CAS 2494-89-5) https://chemicalindependence.com/chemical/2494-89-5/ EPA CompTox (DSSTox): DTXSID0027484. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0027484 PubChem: 75615. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/75615 EPA Chemical Data Reporting: 2494-89-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 2494-89-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293090 for CAS 2494-89-5. Reporting year: 2024. https://usatrade.census.gov/