[3-(Trifluoromethyl)phenyl]acetonitrile

CAS 2338-76-3

Companies reported imports and no US production of this chemical to EPA for 2019.

US productionZero

Import value, 2024$281M

Import volume33.1K lb

Import dependency100%

Top sourceChina 31%

Production is reported production, not a complete census of factories. Production reporting year: 2019. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

[3-(Trifluoromethyl)phenyl]acetonitrile · US import value by year

2013: $339M · Peak 2022: $410M · 2024: $281M · 2025: $254M

Where It Comes From

Customs basis: HS 292690 · basket

EPA reports by year

2019: US production Zero · Imports 33.1K lb

These shares come from HS customs code 292690, which covers 191 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 31%ChinaIT 15%ItalyGB 14%United KingdomIN 11%IndiaJP 8%Japan

South Korea
Spain
Ireland
Ukraine
Malaysia
Brazil
Hong Kong
Latvia
Australia

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Sepro

Why It Matters

Sectors

Agriculture

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing as a reactant

Vendor Pricing

$0.16/gAaron Chemicals LLC

CountryHong Kong

Pack$16.00 / 100 g

Purity96%

Vendors21 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

20 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.18	100 g	96%
Manchester Organics	United Kingdom	$0.29	2.5 kg	97%
Chemscene	United States	$0.29	500 g	—
Combi-Blocks, Inc.	United States	$0.32	1 kg	97%
AstaTech, Inc	United States	$0.34	100 g	98%
A2B Chem LLC	United States	$0.34	1 kg	98%
AA BLOCKS	United States	$0.36	1 kg	98%
MedChemExpress MCE	Sweden	$0.37	500 g	—
Ambeed, Inc.	United States	$0.50	100 g	96%
Apollo Scientific US	United Kingdom	$0.54	100 g	94%
Synthonix	United States	$0.96	25 g	96%
Fluorochem EU	Germany	$0.97	10 g	96%
Fluorochem UK	United Kingdom	$1.00	10 g	96%
Angene International Limited	United States	$1.12	25 g	98%
AK Scientific, Inc.	United States	$1.20	25 g	98%
Sigma-Aldrich (Rush Stock)	Germany	$11.41	10 g	97%
Sigma-Aldrich	Germany	$11.41	10 g	97%
Labotest KG	Germany	$453.00	1000 mg	90%
Key Organics Ltd.	United Kingdom	$1960.00	100 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	96%

Chemical Identity

CAS2338-76-3

PubChem CID75360

DTXSIDDTXSID9044617

FormulaC9H6F3N

Mol. Weight185.15 g/mol

SMILESC1=CC(=CC(=C1)C(F)(F)F)CC#N

Data Sources

EPA CompTox (DSSTox) · DTXSID9044617Retrieved 2026-04-06
PubChem · compound 75360Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

[3-(Trifluoromethyl)phenyl]acetonitrile (CAS 2338-76-3) https://chemicalindependence.com/chemical/2338-76-3/ EPA CompTox (DSSTox): DTXSID9044617. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID9044617 PubChem: 75360. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/75360 EPA Chemical Data Reporting: 2338-76-3. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 2338-76-3. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292690 for CAS 2338-76-3. Reporting year: 2024. https://usatrade.census.gov/