Adagrasib

Drug ingredient

CAS 2326521-71-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$7.6B

Top sourceIreland 61%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India

Israel
Bulgaria
Japan
Spain
Sweden
Canada
Taiwan
Finland
Portugal
Mexico
Belgium
Hungary
Austria
Brazil
Ukraine
Croatia
Malta
South Korea
South Africa
Denmark
Czech Republic
Malaysia
Argentina
Poland
Cameroon
Australia
Hong Kong
Slovakia
Latvia

5 FDA-registered drug labelers

Asymchem Laboratories (Tianjin) Co., Ltd.

Mirati Therapeutics, Inc

PATHEON FRANCE S.A.S

Patheon, Inc.

Syngene International Limited

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Krazati

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$81.80/gAaron Chemicals LLC

CountryHong Kong

Pack$818.00 / 10 g

Purity98%

Vendors20 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

19 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$82.30	10 g	98%
Combi-Blocks, Inc.	United States	$180.00	10 g	98%
A2B Chem LLC	United States	$190.30	10 g	98%
AA BLOCKS	United States	$200.80	10 g	98%
Excenen Pharmatech Co., Ltd	China	$1050.00	1 g	98%
MedKoo Biosciences, Inc	United States	$1190.00	5 g	98%
BLD Pharmatech GmbH	Germany	$1614.00	1 g	98%
BLD Pharmatech Ltd.	China	$1614.00	1 g	98%
Ambeed, Inc.	United States	$1775.00	1 g	98%
Molnova	China	$1792.00	500 mg	99%
AK Scientific, Inc.	United States	$1888.00	1 g	98%
TargetMol Chemicals	China → United States	$1992.00	500 mg	99.9%
BLD Pharmatech Co., Limited	United States	$2844.00	250 mg	98%
Angene International Limited	United States	$2931.00	1 g	98%
MedChemExpress MCE	Sweden	$2937.88	1 g	99.96%
AstaTech, Inc	United States	$3980.00	100 mg	98%
TargetMol Chemicals EU	Austria	$5530.00	100 mg	99.9%
Axon Medchem	Netherlands	$9840.00	50 mg	99%
Cayman Europe	Estonia	$41650.00	10 mg	98%

Chemical Identity

CAS2326521-71-3

PubChem CID138611145

DTXSIDDTXSID801336759

FormulaC32H35ClFN7O2

Mol. Weight604.1 g/mol

SMILESCN1CCCC1COC2=NC3=C(CCN(C3)C4=CC=CC5=C4C(=CC=C5)Cl)C(=N2)N6CCN(C(C6)CC#N)C(=O)C(=C)F

Data Sources

PubChem · compound 138611145Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Health

Brief citations

Adagrasib (CAS 2326521-71-3) https://chemicalindependence.com/chemical/2326521-71-3/ PubChem: 138611145. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/138611145 FDA National Drug Code directory: CAS 2326521-71-3. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293359 for CAS 2326521-71-3. Reporting year: 2024. https://usatrade.census.gov/