Oxymetazoline hydrochloride
Drug ingredientCAS 2315-02-8
This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.
US productionNot reported
Import value, 2024$114M
Top sourceChina 26%
This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.
Why supply is unknownProduction is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 293329 · basket
These shares come from HS customs code 293329, which covers 173 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
Source Countries
Country of origin for US imports, from Census customs data (2024).
CN 26%ChinaIN 17%IndiaKR 16%South KoreaDE 9%GermanyIT 9%Italy
- Australia
- Brazil
- Czech Republic
- Ireland
- Sweden
- Ukraine
- Poland
- United Arab Emirates
- Hungary
- Israel
- Netherlands
- Canada
- Saudi Arabia
- Greece
- Belgium
- Austria
- Latvia
- Singapore
- Denmark
86 FDA-registered drug labelers
A-S Medication Solutions
ALAINA HEALTHCARE PRIVATE LIMITED
Amazon.com Services LLC
American Sales Company
AMERISOURCE BERGEN
Army & Air Force Exchange Service
AX Pharmaceutical Corp.
Bayer HealthCare LLC
BEST CHOICE (VALU MERCHANDISERS COMPANY)
Bi-Mart
BJWC
Cardinal Health 110,Inc
CHAIN DRUG MARKETING ASSOCIATION
CHAIN DRUG MARKETING ASSOCIATION INC
Church & Dwight Co., Inc.
CTX Lifesciences Pvt. Ltd.
CVS Health
CVS Pharmacy
CVS PHARMACY, INC
DARMERICA, LLC
DISCOUNT DRUG MART
DOLGENCORP, INC.
Dolgencorp, LLC
DR. FRIEDMAN'S NO MORE NOSEBLEED KIT INC.
EPI Health, LLC
FAMILY DOLLAR (Family Wellness)
FAMILY DOLLAR SERVICES INC
Foundation Consumer Brands
Genomma Lab USA
Gil Pharmaceutical Corp
H E B
Haleon US Holdings LLC
HyVee Inc
Insight Pharmaceuticals LLC
JC World Bell Wholesale Co., Inc.
Kenvue Brands LLC
KROGER COMPANY
L. Perrigo Company
LETCO MEDICAL, LLC
Lil' Drug Store Products, Inc
Major Pharmaceuticals
MARC GLASSMAN, INC.
Mayne Pharma
MEIJER DISTRIBUTION INC
Meijer, Inc.
Navajo Manufacturing Company Inc.
NeilMed Pharmaceuticals Inc
NuCare Pharmaceuticals, Inc.
Padagis Israel Pharmaceuticals Ltd
Preferred Pharmaceuticals Inc.
Procter & Gamble Manufacturing GmbH
Prodose, Inc.
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
Profounda Inc
PUBLIX SUPER MARKETS, INC
QUALITY CHOICE (CHAIN DRUG MARKETING ASSOCIATION)
RB Health (US) LLC
Reliable 1 Laboratories
Rite Aid Corporation
RVL Pharmaceuticals, Inc.
Safeway
SAFEWAY, INC.
SBS BILIMSEL BIO COZUMLER SANAYI VE TICARET ANONIM SIRKETI PINAR SUBESI
Sheffield Pharmaceuticals LLC
Shodhana Laboratories Private Limited
Siegfried PharmaChemikalien Minden GmbH
Spectrum Laboratory Products, Inc.
Sportpharm LLC
Sportpharm, Inc. dba Sportpharm
Strategic Sourcing Services LLC
Suresource Pharma LLC
Tai Guk Pharm. Co., Ltd.
Target Corporation
Taro Pharmaceuticals U.S.A., Inc.
Topco Associates LLC
United Exchange Corp
United Natural Foods, Inc. dba UNFI
VIVUNT PHARMA LLC
Wal-Mart Stores Inc
Walgreen Company
WALGREENS CO
Walgreens Company
Walmart Inc
WinCo FOODS, LLC
Xlear Inc.
Why It Matters
Sectors
Health
Downstream Uses
Appears in 142 drug and cosmetic product listings (FDA).
- •basic care no drip nasal
- •Quality Choice Nasal Mist Severe Congestion
- •Good Sense Nasal
- •Zicam Intense Sinus Relief
- •Afrin No Drip Severe Congestion
- •nasal
- •Xlear Nasal Decongestant
- •Oxymetazoline Hydrochloride
Show all 142
- •Equaline Nasal
- •Publix Extra Moisturizing
- •Sunmark Nasal Original
- •Sudafed OM Sinus Severe No Drip Nasal Mist with Cooling Menthol
- •Family Wellness Oxymetazoline No Drip
- •DG Health Nasal
- •Vicks Sinex Severe Congestion VapoCOOL Ultra FINE MIST
- •Severe Sinus Relief Mist
- •Oxymethazoline HCL
- •No Drip Severe Nasal Mist
- •CVS Health Ultra Fine Mist
- •CVS Health No Drip
- •Propolis Nasal
- •UP AND UP NO DRIP Nasal
- •Afrin No Drip Extra Moisturizing
- •No Drip
- •Meijer Original
- •No Drip Nasal Mist Nasal Decongestant Severe Congestion
- •Tukol Max Action
- •Oxymetazoline Hydrochloride 12-Hour
- •Discount Drug Mart Original Nasal
- •Family Wellness Oxymetazoline Sinus Severe
- •CVS Health Sinus Relief
- •Family Care Nasal Relief
- •Afrin Original
- •Major Nasal Decongestant
- •Marc Glassman Maximum Strength
- •Sinus Severe Ultra Fine Mist
- •Quality Choicel Nasal Mist Extra Moisturizing
- •Zicam Extreme Congestion Relief
- •Afrin Allergy Sinus Nasal
- •Children Afrin No Drip Extra Moisturizing Stuffy Nose Pump Mist Stuffy Nose Pump Mist
- •Afrin No Drip Original Pump Mist
- •Afrin Severe Congestion
- •nasal decongestant
- •Signature Care Original
- •Topcare Nasal
- •Publix Maximum Strength
- •Family Wellness Oxymetazoline
- •Mucinex Sinus-MAX Severe Congestion Relief Sinus and Allergy
- •Quality Choice Maximum Strength
- •Quality Choice
- •Vicks Sinex Severe Original
- •Circle K Congestion Relief
- •Original Nasal PUMP MIST No Drip
- •No Drip Nasal Mist
- •Kroger No Drip
- •CareOne Severe Congestion Nasal
- •CARE ONE Nasal
- •good neighbor pharmacy nasal
- •Good Neighbor No Drip Nasal Mist Extra Moisturizing
- •Discount Drug Mart Severe Congestion Nasal
- •Family Dollar
- •DG health sinus severe
- •Vicks Sinex Severe Congestion Original Ultra Fine Mist
- •Walgreens Moisturizing Ultra Fine Mist with Aloe
- •Leader Nasal Decongestant
- •Severe Nasal
- •Signature Care Nasal Decongestant
- •Discount drug mart Extra Moisturizing
- •Nostrilla
- •Vicks Sinex Severecongestion Moisturizing Ultra FINE MIST
- •12 Hour Nasal Decongestant Extra Moisturizing
- •berkley and jensen nasal
- •foster and thrive nasal
- •Propolis Nasal PLUS
- •AXIV Sinus Severe Ultra Fine Mist
- •Quality Choice No Drip Nasal Mist
- •Afrin Original Pump Mist
- •SinuFrin NeilMed
- •topcare sinus nasal
- •Publix
- •Discount Drug Mart Maximum Strength Nasal
- •Exchange Select Nasal
- •dg health nasal original
- •Giltuss Severe Sinus
- •BEST Choice No Drip
- •Best Choice
- •Best Choice Ultra Fine Mist
- •Vicks Sinex Severe VapoCOOL Ultra FINE MIST
- •Nasal Spray, 1oz, 24/7 Life by 7-Eleven
- •Nasal Spray, Lil Drug Store
- •Congestion Relief Lil Drug Store Products
- •12 Hour Original Nasal Decongestant
- •CVS Health
- •CVS Health Sinus
- •Equate
- •Quality Choice Nasal
- •Afrin NoDrip Allergy Sinus Night
- •SinuFrin Plus NeilMed
- •oxymetazoline hcl
- •GOOD Neighbor Pharmacy No Drip Nasal Mist
- •Sudafed OM Sinus Severe Original
- •Discount Drug Mart Severe Nasal
- •Vicks Sinex Severe Moisturizing Ultra FINE MIST
- •Severe Congestion Nasal Anti-Drip Nasal Decongestant
- •No Drip Severe Anefrin Nasal
- •CVS Severe Nasal Congestion Relief Clear and Cool
- •Mucinex Sinus Max Sinus Pressure Severe Congestion
- •NO MORE Nosebleed
- •Upneeq
- •Theraflu Severe Congestion Relief Cooling Nasal Mist
- •Dristan 12 hr
- •Children Afrin Extra Moisturizing Stuffy Nose Pump Mist Stuffy Nose Pump Mist
- •care one nasal original
- •CVS Original Nasal Mist
- •Rhofade
- •Mucinex Childrens Stuffy Nose
- •Best Choice Maximum Strength
- •basic care nasal
- •Up and up nasal
- •Kroger No Drip Nasal Mist Severe Congestion
- •nasal 12 hour
- •equate nasal original
- •nasal mist
- •Vicks Sinex Severe Congestion
- •Vicks Sinex Severe Original Ultra FINE MIST
- •Nasal Spray, Circle K
- •Nasal Spray, 24-7 for Life
- •Extra Moisturizing Nasal Pump Mist Anti Drip
- •Rhinase D Gel Moisturizing Nasal Decongestant
- •Walgreen
- •Afrin Original Nasal
- •Afrin No-Drip Allergy Sinus
- •AVON HeXashield Congestion Relief Original
- •Equate Nasal
- •Sudafed OM Sinus Severe No Drip Nasal Mist
- •Ultra Fine Mist Sinus Relief
- •Mucinex Sinus-MAX Severe Nasal Congestion Relief Clear and COOL Nasal
- •Afrin
- •Anefrin Nasal Original
- •Maximum Strength Nasal Decongestant
- •Mucinex Sinus Max Clear and Cool Severe Congestion
- •Theraflu Severe Congestion Relief Nasal Mist
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Vendor Pricing
$19.12/gAK Scientific, Inc.
CountryUnited States
Pack$478.00 / 25 g
Purity98%
Vendors10 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
9 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| Sigma-Aldrich (Rush Stock) | Germany | $35.33 | 5 g | 99% |
| Sigma-Aldrich | Germany | $35.33 | 5 g | 99% |
| MedKoo Biosciences, Inc | United States | $38.50 | 100 g | 98% |
| Cayman Europe | Estonia | $145.18 | 1 g | 95% |
| CliniSciences GmbH | Switzerland | $322.50 | 100 mg | 99% |
| Apexbio Technology LLC | United States | $1080.00 | 100 mg | 95% |
| AK Scientific Specialized | United States | $1530.00 | 100 mg | 99% |
| Otava, Ltd. (2 weeks) | Ukraine | $2724.00 | 50 mg | 90% |
| TimTec, LLC | United States | $9333.33 | 30 mg | 99% |
Chemical Identity
CAS2315-02-8
PubChem CID66259
DTXSIDDTXSID80177729
FormulaC16H25ClN2O
Mol. Weight296.83 g/mol
SMILESCC1=CC(=C(C(=C1CC2=NCCN2)C)O)C(C)(C)C.Cl
Data Sources
- PubChem · compound 66259Retrieved 2026-04-07
- FDA National Drug Code directoryRetrieved 2026-04-25
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Oxymetazoline hydrochloride (CAS 2315-02-8) https://chemicalindependence.com/chemical/2315-02-8/ PubChem: 66259. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/66259 FDA National Drug Code directory: CAS 2315-02-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293329 for CAS 2315-02-8. Reporting year: 2024. https://usatrade.census.gov/