Miconazole

Drug ingredient

CAS 22916-47-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$114M

Top sourceChina 26%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293329 · basket

These shares come from HS customs code 293329, which covers 173 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 26%ChinaIN 17%IndiaKR 16%South KoreaDE 9%GermanyIT 9%Italy

Australia
Brazil
Czech Republic
Ireland
Sweden
Ukraine
Poland
United Arab Emirates
Hungary
Israel
Netherlands
Canada
Saudi Arabia
Greece
Belgium
Austria
Latvia
Singapore
Denmark

10 FDA-registered drug labelers

Galt Pharmaceuticals, LLC

Jiangxi Yudexi Pharmaceutical Co., LTD

Natouch LLC

Olon S.p.A.

Professional Compounding Centers of America

Professional Compounding Centers of America dba PCCA

Spectrum Laboratory Products, Inc.

VIVE HEALTH LLC

YUNG ZIP CHEMICAL INDUSTRIAL CO., LTD.

Zen Chemicals Private Limited

Why It Matters

Sectors

Health

Downstream Uses

Appears in 5 drug and cosmetic product listings (FDA).

•Healmusz Clotrimazole
•natouch
•Antifungal
•Antifungal Ringworm Cream
•Oravig

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$1.28/gCombi-Blocks, Inc.

CountryUnited States

Pack$640.00 / 500 g

Purity97%

Vendors18 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

17 more vendors

Vendor	Country	$/g	Pack	Purity
A2B Chem LLC	United States	$1.36	500 g	97%
AA BLOCKS	United States	$1.44	500 g	98%
AK Scientific Specialized	United States	$2.21	100 g	95%
AstaTech, Inc	United States	$2.28	25 g	97%
AK Scientific, Inc.	United States	$2.97	100 g	98%
Angene Chemical	China → Hong Kong	$3.48	100 g	99%
Aaron Chemicals LLC	Hong Kong	$3.62	100 g	99%
Fulfilled by Molport	Latvia	$12.00	500 mg	—
Apexbio Technology LLC	United States	$20.00	5 g	99.84%
Angene International Limited	United States	$20.40	5 g	99%
MedKoo Biosciences, Inc	United States	$22.00	25 g	98%
Molnova	China	$70.00	500 mg	99%
TargetMol Chemicals	China → United States	$78.00	500 mg	99.99%
MedChemExpress MCE	Sweden	$125.84	500 mg	99.97%
Labotest KG	Germany	$217.80	5000 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	99%
Key Organics Ltd.	United Kingdom	$6900.00	10 mg	97%

Chemical Identity

CAS22916-47-8

PubChem CID4189

DTXSIDDTXSID6023319

FormulaC18H14Cl4N2O

Mol. Weight416.1 g/mol

SMILESC1=CC(=C(C=C1Cl)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl

Data Sources

PubChem · compound 4189Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Miconazole (CAS 22916-47-8) https://chemicalindependence.com/chemical/22916-47-8/ PubChem: 4189. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/4189 FDA National Drug Code directory: CAS 22916-47-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293329 for CAS 22916-47-8. Reporting year: 2024. https://usatrade.census.gov/