Benzenesulfonamide, N-phenyl-N-[(trichloromethyl)thio]-

CAS 2280-49-1

EPA’s 2023 records show zero U.S. production of this chemical.

US productionZero

Import value, 2024$2.0B

Import volumeCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Top sourceIreland 63%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

EPA reports by year

2023: US production Zero · Imports Confidential
2019: US production Zero · Imports 308.3K lb

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland

Portugal
Spain
Italy
Austria
Israel
Hungary
Canada
South Korea
Netherlands
Finland
Poland
Indonesia
Ukraine
Mexico
South Africa
Croatia
Greece
Taiwan
Hong Kong

EPA-registered importers (5)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Safic-Alcan · FR France

Akrochem

Chemspec

Flow Polymers

Lanxess

Why It Matters

Sectors

Plastics & RubberConsumer ProductsPaints & CoatingsCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 2 sectors as 2 functional roles.

•Polymerization promoter in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Chemical reaction regulator in Rubber Product Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$756.00/gA2B Chem LLC (1 week)

CountryUnited States

Pack$756.00 / 1 g

Purity95%

Vendors2 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

1 more vendor

Vendor	Country	$/g	Pack	Purity
AA BLOCKS (1 week)	United States	$800.00	1 g	95%

Chemical Identity

CAS2280-49-1

PubChem CID75290

DTXSIDDTXSID4062303

FormulaC13H10Cl3NO2S2

Mol. Weight382.7 g/mol

SMILESC1=CC=C(C=C1)N(SC(Cl)(Cl)Cl)S(=O)(=O)C2=CC=CC=C2

Data Sources

EPA CompTox (DSSTox) · DTXSID4062303Retrieved 2026-04-06
PubChem · compound 75290Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Benzenesulfonamide, N-phenyl-N-[(trichloromethyl)thio]- (CAS 2280-49-1) https://chemicalindependence.com/chemical/2280-49-1/ EPA CompTox (DSSTox): DTXSID4062303. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID4062303 PubChem: 75290. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/75290 EPA Chemical Data Reporting: 2280-49-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 2280-49-1. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293590 for CAS 2280-49-1. Reporting year: 2024. https://usatrade.census.gov/