Diflunisal

Drug ingredient

CAS 22494-42-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 22494-42-4
US productionNot reported
Import value, 2024$122M
Top sourceSouth Korea 39%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291829 · basket

These shares come from HS customs code 291829, which covers 85 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
KR 39%South KoreaCN 26%ChinaTW 11%TaiwanJP 9%JapanSG 5%Singapore
10 FDA-registered drug labelers
Aarti Pharmalabs Limited
Apicore Pharmaceuticals Private Limited
Chartwell RX, LLC
COHANCE LIFESCIENCES LIMITED
Emcure Pharmaceuticals Limited
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
INA Pharmaceutics Inc
Teva Pharmaceuticals USA, Inc.
Zydus Lifesciences Limited
Zydus Pharmaceuticals (USA) Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

  • •diflunisal
  • •Dolobid
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.98/gA2B Chem LLC
CountryUnited States
Pack$98.00 / 100 g
Purity98%
Vendors30 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS22494-42-4
PubChem CID3059
DTXSIDDTXSID5022932
FormulaC13H8F2O3
Mol. Weight250.2 g/mol
SMILESC1=CC(=C(C=C1C2=C(C=C(C=C2)F)F)C(=O)O)O

Data Sources

Brief citations

Diflunisal (CAS 22494-42-4) https://chemicalindependence.com/chemical/22494-42-4/ PubChem: 3059. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/3059 FDA National Drug Code directory: CAS 22494-42-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291829 for CAS 22494-42-4. Reporting year: 2024. https://usatrade.census.gov/