Vardenafil

Drug ingredient

CAS 224785-90-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$2.0B

Top sourceIreland 63%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland

Portugal
Spain
Italy
Austria
Israel
Hungary
Canada
South Korea
Netherlands
Finland
Poland
Indonesia
Ukraine
Mexico
South Africa
Croatia
Greece
Taiwan
Hong Kong

3 FDA-registered drug labelers

Guangzhou Yixin Cross-border E-commerce Co., Ltd.

Macleods Pharmaceuticals Limited

Xinshu Technology Co., Limited

Why It Matters

Sectors

Health

Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

•Esokalli Testosterone Booster Oral Dissolving Film
•Vardenafil Hydrochloride
•CHBO

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$10.36/gA2B Chem LLC

CountryUnited States

Pack$259.00 / 25 g

Purity98%

Vendors11 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

10 more vendors

Vendor	Country	$/g	Pack	Purity
AA BLOCKS	United States	$10.96	25 g	98%
Angene Chemical	China → Hong Kong	$31.00	10 g	99%
Combi-Blocks, Inc.	United States	$33.60	25 g	98%
Aaron Chemicals LLC	Hong Kong	$33.80	5 g	99%
Biopharma PEG Scientific Inc.	United States	$175.00	1 g	95%
TargetMol Chemicals	China → United States	$238.00	1 g	99.88%
TargetMol Chemicals EU	Austria	$324.00	500 mg	99.88%
Apexbio Technology LLC	United States	$920.00	100 mg	99.98%
Angene	China → Hong Kong	$4266.67	30 mg	98%
Angene International Limited	United States	$12230.00	100 mg	98%

Chemical Identity

CAS224785-90-4

PubChem CID135400189

DTXSIDDTXSID3048318

FormulaC23H32N6O4S

Mol. Weight488.6 g/mol

SMILESCCCC1=NC(=C2N1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)CC)OCC)C

Data Sources

PubChem · compound 135400189Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Vardenafil (CAS 224785-90-4) https://chemicalindependence.com/chemical/224785-90-4/ PubChem: 135400189. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/135400189 FDA National Drug Code directory: CAS 224785-90-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293590 for CAS 224785-90-4. Reporting year: 2024. https://usatrade.census.gov/