fluciclovine f-18

Drug ingredient

CAS 222727-39-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$941M

Top sourceCanada 61%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 284443 · basket

These shares come from HS customs code 284443, which covers 14 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CA 61%CanadaNL 12%NetherlandsDE 8%GermanyIT 7%ItalyBE 3%Belgium

Australia
Finland
United Kingdom
Norway
Uzbekistan
Switzerland
Israel
Brazil
Poland
Kazakhstan
Libya
Japan
China
Denmark
Spain
Hungary
United Arab Emirates
Singapore
Oman
Colombia

1 FDA-registered drug labeler

Blue Earth Diagnostics

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Axumin

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$368.60/gA2B Chem LLC

CountryUnited States

Pack$1843.00 / 5 g

Purity95%

Vendors14 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

13 more vendors

Vendor	Country	$/g	Pack	Purity
Combi-Blocks, Inc.	United States	$378.70	10 g	95%
PharmaBlock US	United States	$379.80	5 g	97%
AA BLOCKS	United States	$387.60	5 g	95%
SpiroChem (2 weeks)	Switzerland	$412.48	10 g	95%
Aaron Chemicals LLC	Hong Kong	$481.00	1 g	97%
Angene Chemical	China → Hong Kong	$561.00	1 g	97%
BLD Pharmatech Ltd.	China	$575.00	1 g	95%
AstaTech, Inc	United States	$798.00	1 g	95%
Synthonix	United States	$800.00	1 g	95%
A2B Chem LLC (2 weeks)	United States	$1450.00	1 g	97%
AA BLOCKS (2 weeks)	United States	$1485.00	1 g	97%
Combi-Blocks (back-ordered)	United States	$2295.00	1 g	95%
Angene International Limited	United States	$2512.00	250 mg	95%

Chemical Identity

CAS222727-39-1

PubChem CID450601

DTXSIDDTXSID601027796

FormulaC5H8FNO2

Mol. Weight132.12 g/mol

SMILESC1C(CC1(C(=O)O)N)F

Data Sources

PubChem · compound 450601Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

fluciclovine f-18 (CAS 222727-39-1) https://chemicalindependence.com/chemical/222727-39-1/ PubChem: 450601. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/450601 FDA National Drug Code directory: CAS 222727-39-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 284443 for CAS 222727-39-1. Reporting year: 2024. https://usatrade.census.gov/