silver sulfadiazine

Drug ingredient

CAS 22199-08-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 22199-08-2 — 1 Ag⁺

US productionNot reported

Import value, 2024$3M

Top sourceCroatia 58%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 284329 · basket

These shares come from HS customs code 284329, which covers 28 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

HR 58%CroatiaGB 20%United KingdomJP 7%JapanES 6%SpainIN 3%India

North Macedonia
Taiwan
Malaysia
Saudi Arabia
Mexico
Czech Republic

18 FDA-registered drug labelers

A-S Medication Solutions

Advanced Rx Pharmacy of Tennessee, LLC

Ascend Laboratories, LLC

Asclemed USA, Inc.

Bryant Ranch Prepack

DIRECT RX

Dr Reddys Laboratories Inc

Lusochimica SPA

MACSEN DRUGS

Mylan Pharmaceuticals Inc.

NuCare Pharmaceuticals, Inc.

Pfizer Laboratories Div Pfizer Inc

Preferred Pharmaceuticals Inc.

Proficient Rx LP

Spectrum Laboratory Products, Inc.

Srikem Laboratories Pvt. Ltd.

ST. MARY'S MEDICAL PARK PHARMACY

TAPI Croatia Industries Ltd.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 5 drug and cosmetic product listings (FDA).

•Silver Sulfadiazine
•Silvadene
•SSD Cream
•SSD
•Thermazene Silver Sulfadiazine

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$3.35/gAK Scientific Specialized

CountryUnited States

Pack$335.00 / 100 g

Purity95%

Vendors11 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

10 more vendors

Vendor	Country	$/g	Pack	Purity
BLD Pharmatech GmbH	Germany	$3.60	25 g	97%
AK Scientific, Inc.	United States	$4.49	100 g	98%
Fulfilled by Molport	Latvia	$5.00	5 g	—
BLD Pharmatech Ltd.	China	$5.00	5 g	97%
BLD Pharmatech Co., Limited	United States	$10.00	1 g	97%
Ambeed, Inc.	United States	$10.00	1 g	97%
AstaTech (2 weeks)	United States	$10.16	25 g	95%
Molnova	China	$100.00	500 mg	99%
Vitas M Chemical Limited	Hong Kong	$360.00	1 g	90%
Key Organics Ltd.	United Kingdom	$1960.00	100 mg	99%

Chemical Identity

CAS22199-08-2

PubChem CID441244

DTXSIDDTXSID4048646

FormulaC10H9AgN4O2S

Mol. Weight357.14 g/mol

SMILESC1=CN=C(N=C1)[N-]S(=O)(=O)C2=CC=C(C=C2)N.[Ag+]

Data Sources

PubChem · compound 441244Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

silver sulfadiazine (CAS 22199-08-2) https://chemicalindependence.com/chemical/22199-08-2/ PubChem: 441244. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/441244 FDA National Drug Code directory: CAS 22199-08-2. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 284329 for CAS 22199-08-2. Reporting year: 2024. https://usatrade.census.gov/