Cyprosulfamide

CAS 221667-31-8

EPA’s 2023 records show zero U.S. production of this chemical.

US productionZero

Import value, 2024$2.0B

Import volumeCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Top sourceIreland 63%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

EPA reports by year

2023: US production Zero · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland

Portugal
Spain
Italy
Austria
Israel
Hungary
Canada
South Korea
Netherlands
Finland
Poland
Indonesia
Ukraine
Mexico
South Africa
Croatia
Greece
Taiwan
Hong Kong

EPA-registered importers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Bayer Ag · DE Germany

Bayer Us Holding

Why It Matters

Sectors

Agriculture

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing as a reactant

Vendor Pricing

$177.10/gAaron Chemicals LLC

CountryHong Kong

Pack$1771.00 / 10 g

Purity95%

Vendors8 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

7 more vendors

Vendor	Country	$/g	Pack	Purity
A2B Chem LLC (1 week)	United States	$659.00	1 g	95%
AA BLOCKS (1 week)	United States	$733.00	1 g	95%
Combi-Blocks, Inc.	United States	$800.00	1 g	95%
Angene Chemical	China → Hong Kong	$1000.00	1 g	95%
AstaTech (2 weeks)	United States	$1054.00	1 g	95%
Sigma-Aldrich (Rush Stock)	Germany	$1287.60	100 mg	—
Sigma-Aldrich	Germany	$1287.60	100 mg	—

Chemical Identity

CAS221667-31-8

PubChem CID11707647

DTXSIDDTXSID9058022

FormulaC18H18N2O5S

Mol. Weight374.4 g/mol

SMILESCOC1=CC=CC=C1C(=O)NS(=O)(=O)C2=CC=C(C=C2)C(=O)NC3CC3

Data Sources

EPA CompTox (DSSTox) · DTXSID9058022Retrieved 2026-04-06
PubChem · compound 11707647Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Cyprosulfamide (CAS 221667-31-8) https://chemicalindependence.com/chemical/221667-31-8/ EPA CompTox (DSSTox): DTXSID9058022. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID9058022 PubChem: 11707647. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/11707647 EPA Chemical Data Reporting: 221667-31-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 221667-31-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293590 for CAS 221667-31-8. Reporting year: 2024. https://usatrade.census.gov/