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Nifedipine

Drug ingredient

CAS 21829-25-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 21829-25-4
US productionNot reported
Import value, 2024$1.3B
Top sourceChina 32%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293339 · basket

These shares come from HS customs code 293339, which covers 397 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 32%ChinaIN 15%IndiaDE 10%GermanyBE 9%BelgiumCH 8%Switzerland
49 FDA-registered drug labelers
A-S Medication Solutions
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
American Health Packaging
Aphena Pharma Solutions - Tennessee, LLC
Ascend Laboratories, LLC
Aurobindo Pharma Limited
AvPAK
Bayer AG
Bryant Ranch Prepack
Cardinal Health 107, LLC
Catalent Pharma Solutions, LLC
Chartwell RX, LLC
DARMERICA, LLC
Dipharma Francis Srl
Elite Pharmaceutical Solution, Inc.
F.I.S. Fabbrica Italiana Sintetici S.P.A.
Fagron Inc
Golden State Medical Supply, Inc.
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
Ingenus Pharmaceuticals, LLC
Kalchem International inc
Lannett Company, Inc.
Leading Pharma, LLC
LETCO MEDICAL, LLC
Major Pharmaceuticals
Medisca Inc.
Moehs Catalana SL
NCS HealthCare of KY, LLC dba Vangard Labs
Northwind Health Company, LLC
NuCare Pharmaceuticals,Inc.
Oceanside Pharmaceuticals
PD-Rx Pharmaceuticals, Inc.
Pfizer Laboratories Div Pfizer Inc
Preferred Pharmaceuticals Inc.
Professional Compounding Centers of America
Proficient Rx LP
Redpharm Drug
REMEDYREPACK INC.
Sharon Bio-Medicine Limited
SHILPA PHARMA LIFESCIENCES LIMITED
SICOR Societa' Italiana Corticosteroidi s.r.l.
ST. MARY'S MEDICAL PARK PHARMACY
Unique Chemicals
Upsher-Smith Laboratories, LLC
Viatris Pharmaceuticals LLC
Xenex Laboratories Inc
Zydus Lifesciences Limited
Zydus Pharmaceuticals (USA) Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

  • •Nifedipine
  • •Procardia XL
  • •Nifedipine ER
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.14/gAaron Chemicals LLC
CountryHong Kong
Pack$136.00 / 1 kg
Purity98%
Vendors35 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

34 more vendors
VendorCountry$/gPackPurity
Angene ChemicalChina → Hong Kong$0.141 kg98%
AA BLOCKSUnited States$0.181 kg98%
A2B Chem LLCUnited States$0.19500 g98%
BLD Pharmatech GmbHGermany$0.211 kg98%
BLD Pharmatech Ltd.China$0.211 kg98%
Ambeed, Inc.United States$0.231 kg98%
Combi-Blocks, Inc.United States$0.251 kg98%
BLD Pharmatech Co., LimitedUnited States$0.27500 g98%
AK Scientific SpecializedUnited States$0.70100 g95%
AstaTech, IncUnited States$1.1625 g95%
Fluorochem EUGermany$1.2110 g96%
AK Scientific, Inc.United States$3.31100 g98%
Angene International LimitedUnited States$4.00250 g98%
Fluorochem UKUnited Kingdom$7.151 g96%
Cayman EuropeEstonia$10.0010 g98%
Fulfilled by MolportLatvia$10.00500 mg99.49%
Apexbio Technology LLCUnited States$11.1010 g98.37%
MedChemExpress MCESweden$16.4610 g99.9%
Sigma-Aldrich (Rush Stock)Germany$33.3425 g98%
Sigma-AldrichGermany$33.3425 g98%
MolnovaChina$48.001 g99%
TargetMol ChemicalsChina → United States$53.001 g99.49%
MedKoo Biosciences, IncUnited States$75.0010 g98%
Vitas M Chemical LimitedHong Kong$306.001 g90%
CliniSciences GmbHSwitzerland$322.50100 mg99%
Labotest KGGermany$453.001000 mg90%
Axon MedchemNetherlands$696.00250 mg99%
Maybridge, Ltd.United Kingdom$2414.30100 mg90%
Otava, Ltd. (2 weeks)Ukraine$2724.0050 mg90%
Princeton BioMolecular Research (SC)United States$2900.00100 mg90%
AngeneChina → Hong Kong$4266.6730 mg98%
Life Chemicals Inc.Ukraine → Canada$4500.0040 mg90%
Key Organics Ltd.United Kingdom$6900.0010 mg97%
TimTec, LLCUnited States$9333.3330 mg98%

Chemical Identity

CAS21829-25-4
PubChem CID4485
DTXSIDDTXSID2025715
FormulaC17H18N2O6
Mol. Weight346.3 g/mol
SMILESCC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC

Data Sources

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Brief citations

Nifedipine (CAS 21829-25-4) https://chemicalindependence.com/chemical/21829-25-4/ PubChem: 4485. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/4485 FDA National Drug Code directory: CAS 21829-25-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293339 for CAS 21829-25-4. Reporting year: 2024. https://usatrade.census.gov/