Aluminum hydroxide
Drug ingredientCAS 21645-51-2
This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$251M
Top sourceBrazil 48%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 281830 · narrow
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
These shares come from HS customs code 281830, which covers 3 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
Source Countries
Country of origin for US imports, from Census customs data (2024).
BR 48%BrazilCA 17%CanadaJM 10%JamaicaDE 9%GermanyDK 6%Denmark
- India
- Belgium
- Spain
- Australia
- United Kingdom
- Turkey
- Greece
- Mexico
- Bosnia and Herzegovina
EPA-registered manufacturers (9)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Chemtrade Logistics · CA Canada
Daelim · KR South Korea
Chemmasters
Chemtrade Holdco Us
Kraton
Show all 9
Minerals Technologies
Rio Tinto America Holdings
Spirit Aerosystems
Tredegar
Domestic parents -- activity not disclosed (15)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
Basf
Brenntag
Chemours
Chemtrade Chemicals Us
Coorstek
Show all 15
Flint Cps Inks North America
Henkel
Munzing
Polynt Composites Usa
Scott Bader
Teknor Apex
The Terra Firma Company (De)
Usal
Vibrantz Technologies
Wacker Chemical Corporation - Headquarters
EPA-registered importers (43)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Basf Se · DE Germany
Clariant International · CH Switzerland
Heubach Holding S R L · LU Luxembourg
Heubach Holdings Sarl · LU Luxembourg
Ibg Industrie-Beteiligungs-Gesellschaft Mbh & Co Kg · DE Germany
Show all 43
Ishihara Sangyo Kaisha · JP Japan
Orbia Advance Corp S A B De C V · MX Mexico
Ravago S A · LU Luxembourg
Sika Ag · CH Switzerland
Sumitomo Bakelite · JP Japan
3M
Akzo Nobel Coatings
Alphagary
Aoc
Autoliv Promontory
Avient
Blachford
Blue Tree Holdings
Cellmark Usa
Cht Usa
Clariant
Dow Chemical
Hct
Heubach Holding Usa
Isk Americas Incorporated
Jm Huber
Johnson Matthey
Kemper System America
Lanxess
Lx Hausys America
Ngk Ceramics Usa
Nippon Paint Automotive Americas
O'Sullivan Films
Parker-Hannifin
Pigments Services
Sensient Colors
Shin Etsu Silicones Of America
Sika
Smalticeram Usa
Southern Ionics
Sumitomo Plastics America
The Sherwin Williams
W. R. Grace & Co. - Conn.
64 FDA-registered drug labelers
A-S Medication Solutions
American Health Packaging
Amerisource Bergen
AMERISOURCEBERGEN DRUG CORPORATION
ATLANTIC BIOLOGICALS CORP.
Beijing Keyan Biotechnology Co., Ltd.
Belleview Bioscience LLC
Belmora LLC
BETTER LIVING BRANDS LLC
CARDINAL HEALTH
Cardinal Health 107, LLC
CHAIN DRUG MARKETING ASSOCIATION
CHAIN DRUG MARKETING ASSOCIATION INC.
CVS
CVS PHARMACY
CVS PHARMACY,INC.
DOLGENCORP, LLC
Elementis Pharma Gmbh
Everpharm LLC
FORTUNE PHARMACAL COMPANY LIMITED
GERI-CARE PHARMACEUTICALS, CORP
GOODSENSE
H E B
Haleon US Holdings LLC
Harris Teeter, LLC
Infirst Healthcare Inc.
Kesin Pharma Corporation
KROGER COMPANY
Major Pharmaceuticals
MAJOR Pharmaceuticals Inc.
MEIJER DISTRIBUTION INC
Meijer, Inc.
NuCare Pharmaceuticals, Inc.
PADARSH PHARMACEUTICALS PVT. LTD
PAI Holdings, LLC
PAI Holdings, LLC dba PAI Pharma
PHARMACY VALUE ALLIANCE, LLC
Preferred Pharmaceuticals Inc.
Professional Compounding Centers of America
Proficient Rx LP
Retail Business Services, LLC.
Rising Pharma Holdings, Inc.
RITE AID CORPORATION
RITE AID PHARMACY
RUGBY LABORATORIES
Safeway
Sato Pharmaceutical Co., Ltd.
SEIL INTERNATIONAL LTD
Simpex Pharma Pvt. Ltd
SPI PHARMA
SPI PHARMA Inc.
STRATEGIC SOURCING SERVICES LLC
TARGET CORPORATION
THE KROGER CO.,
Topco Associates, LLC
Twin Med LLC
UNITED NATURAL FOODS, INC. DBA UNFI
VALU MERCHANDISERS COMPANY
Vasundhara Rasayans Limited
WAL-MART STORES, INC.
WALGREEN CO.
WALGREEN COMPANY
WellSpring Pharmaceutical Corporation
Willow Birch Pharma, LLC
Why It Matters
Sectors
FoodPlastics & RubberPaints & CoatingsElectronicsTransportationPaper & PrintingDefenseCore ChemicalsHealthEnergyConsumer ProductsMetals & MiningWaterTextilesConstruction
Downstream Uses
Appears in 75 drug and cosmetic product listings (FDA).
- •Regular Strength Antacid/Antigas
- •Maximum Strength Antacid and Antigas
- •Melox
- •Mag-AL Plus
- •maximum strength antacid cherry
- •ProCure DryDrox
- •Aluminum Hydroxide, Magnesium Hydroxide and Simethicone
- •Maximum Strength Antacid AND Antigas Cherry
Show all 75
- •Mintox Maximum Strength
- •Walgreens Fast Acting Heartburn Relief Extra Strength
- •Antacid MINT
- •Extra Strength Antacid Original Flavor
- •Antacid Antigas
- •Aluminum Hydroxide
- •ONE Percent Sunscreen
- •Acid Gone Antacid Extra Strength
- •Maximum Strength Antacid
- •Regular Strength Antacid Mint
- •GOOD Neighbor Pharmacy Antacid Extra Strength
- •GERI-Lanta Antacid
- •Maximum Strength Advanced Antacid
- •Heartburn Relief
- •FAST Acting Heartburn Relief
- •Maximum Strength Antacid Antigas
- •Kesin MAG-AL Plus
- •Rite Aid Extra Strength
- •Antacid
- •Gaviscon
- •HEB Extra Strength Cool Mint
- •Antacid AND Gasrelief
- •GERI-MOX MAX Cherry
- •GERI-Lanta Maximum Strength
- •Regular Strength Antacid
- •Maximum Strength Antacid MINT
- •Aluminum Hydroxide, Magnesium Hydroxide and Simethicone Suspension
- •Regular Strength Antacid AND GAS Relief
- •Mag-AL Plus XS
- •HEB Extra Strength Cherry Flavor
- •Maximum Strength Antacid AND Gasrelief
- •Gelusil
- •CVS Health Extra Strength Antacid
- •Aluminum hydroxide and Magnesium carbonate
- •ACID GONE Antacid
- •Gaviscon Extra Strength
- •INON
- •KO-Lanta
- •Mylanta Maximum Strength Vanilla Caramel Flavor
- •Kroger Extra Strength
- •Mag-AL Liquid
- •Antacid Antigas NTA
- •GERI-Lanta Antacid Antigas
- •GERI-MOX Antacid Antigas
- •Almacone Double Strength
- •Kesin MAG-AL Plus XS
- •Mintox Plus Tabs
- •Maximum Strength Antacid Cherry liquid
- •CVS Pharmacy Extra Strength Cherry Flavor
- •Mylanta Maximum Strength Classic Flavor
- •Premier Value Extra Strength Original Flavor
- •Regular Strength Antacid AND Antigas
- •Kesin MAG-AL
- •QCH Regular Strength Antacid 509
- •Extra Strength Antacid
- •Meijer Extra Strength Original Flavor
- •equate Extra Strength Antacid
- •Advanced Antacid MINT
- •CVS Health Extra Strength Heartburn Relief Antacid Original Flavor
- •Aluminum Hydroxide, Magnesium Hydroxide, and Dimethicone
- •Extra Strength Heartburn Relief
- •QCH Maximum Strength Antacid 516
- •Quality Choice Original Flavor
- •HEB Extra Strength Original Flavor
- •Magsil Antacid (Lemon MINT)
- •Antacid Plus
- •Advanced Regular Strength Antacid
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 36 sectors as 25 functional roles.
- •Pigment in Printing Ink Manufacturing (12%)Processing—incorporation into formulation, mixture, or reaction product
- •Pigment in Plastics Material and Resin Manufacturing (2%)Processing—incorporation into formulation, mixture, or reaction product
- •Pigment in Plastics Product Manufacturing (19%)Processing—incorporation into formulation, mixture, or reaction product
- •Pigment in Wholesale and Retail Trade (6%)Processing—incorporation into formulation, mixture, or reaction product
- •Pigment in Asphalt Paving, Roofing, and Coating Materials Manufacturing (11%)Processing—incorporation into formulation, mixture, or reaction product
- •Pigment in Paint and Coating Manufacturing (50%)Processing—incorporation into formulation, mixture, or reaction product
- •Flocculating agent in Other (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Sealant (barrier) in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Plastics Material and Resin Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Printing Ink ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Filler in Printing and Related Support ActivitiesProcessing—repackaging
- •Crystal growth modifiers (nucleating agents) in Transportation Equipment Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in All Other Basic Inorganic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Filler in Construction (10%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Food, beverage, and tobacco product manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Flocculating agent in All Other Basic Inorganic Chemical Manufacturing (30%)Processing—incorporation into formulation, mixture, or reaction product
- •Flux agent in All Other Basic Inorganic Chemical Manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product
- •Solids separation (precipitating) agent, not otherwise specified in All Other Basic Inorganic Chemical Manufacturing (0%)Processing as a reactant
- •Ion exchange agent in Petroleum Refineries (20%)Processing—incorporation into formulation, mixture, or reaction product
- •Pigment in Construction (50%)Processing—incorporation into formulation, mixture, or reaction product
- •Pigment in Custom Compounding of Purchased Resins (50%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Fabricated Metal Product Manufacturing (24%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Computer and Electronic Product Manufacturing (24%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Machinery Manufacturing (8%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Transportation Equipment Manufacturing (24%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Electrical Equipment, Appliance, and Component Manufacturing (8%)Processing—incorporation into formulation, mixture, or reaction product
- •Dye in Food, beverage, and tobacco product manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Adhesive Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Sealant (barrier) in Electrical Equipment, Appliance, and Component Manufacturing (100%)Processing—incorporation into article
- •Binder in All Other Basic Inorganic Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Thickening agent in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Flame retardant in Services (20%)Processing—incorporation into article
- •Flame retardant in Fabricated Metal Product Manufacturing (1%)Processing—incorporation into article
- •Flame retardant in Primary Metal Manufacturing (9%)Processing—incorporation into article
- •Flame retardant in Computer and Electronic Product Manufacturing (4%)Processing—incorporation into article
- •Flame retardant in Transportation Equipment Manufacturing (9%)Processing—incorporation into article
- •Flame retardant in Custom Compounding of Purchased Resins (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Flame retardant in Electrical Equipment, Appliance, and Component Manufacturing (57%)Processing—incorporation into article
- •Flocculating agent in Utilities (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Primary Metal ManufacturingProcessing as a reactant
- •Pigment in Paper Manufacturing (1%)Processing—incorporation into article
- •Pigment in Transportation Equipment Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Stabilizing agent in Printing Ink Manufacturing (50%)Processing—incorporation into formulation, mixture, or reaction product
- •Stabilizing agent in Miscellaneous Manufacturing (50%)Processing—incorporation into article
- •Stabilizing agent in Construction (50%)Processing—incorporation into article
- •Stabilizing agent in Paint and Coating Manufacturing (50%)Processing—incorporation into formulation, mixture, or reaction product
- •Surface modifier in Machinery ManufacturingProcessing—incorporation into article
- •Filler in Wood Product ManufacturingProcessing—incorporation into article
- •Surface modifier in Transportation Equipment ManufacturingProcessing—incorporation into article
- •Surface modifier in Electrical Equipment, Appliance, and Component ManufacturingProcessing—incorporation into article
- •Filler in Furniture and Related Product ManufacturingProcessing—incorporation into article
- •Surface modifier in Miscellaneous ManufacturingProcessing—incorporation into article
- •Filler in Paint and Coating ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Fixing agent (mordant) in Printing and Related Support Activities (60%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Miscellaneous Manufacturing (0%)Processing—incorporation into article
- •Flame retardant in Miscellaneous Manufacturing (0%)Processing—incorporation into article
- •Surface modifier in Other (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Insulators in Other (80%)Processing—incorporation into article
- •Abrasives in Miscellaneous Manufacturing (0%)Processing as a reactant
- •Filler in Rubber Product ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Plating agent in Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Plastics Product Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Textiles, apparel, and leather manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in All Other Chemical Product and Preparation Manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product
- •Catalyst in Industrial Gas Manufacturing (2%)Use—non-incorporative activities
- •Catalyst in All Other Chemical Product and Preparation Manufacturing (52%)Use—non-incorporative activities
- •Adsorbent in Petroleum Refineries (45%)Use—non-incorporative activities
- •Plasticizer in Primary Metal Manufacturing (100%)Processing—incorporation into article
- •Monomers in Plastics Material and Resin ManufacturingProcessing—incorporation into article
- •Abrasives in Not Known or Reasonably Ascertainable (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Filler in Not Known or Reasonably AscertainableProcessing—incorporation into formulation, mixture, or reaction product
- •Flame retardant in Plastics Product Manufacturing (10%)Processing—incorporation into article
- •Flame retardant in Plastics Material and Resin Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Surface modifier in Fabricated Metal Product Manufacturing (0%)Processing—incorporation into article
- •Catalyst in All Other Basic Organic Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Dispersing agent in Paint and Coating Manufacturing (0%)Processing—incorporation into article
- •Catalyst in Petrochemical ManufacturingProcessing—incorporation into article
- •Filler in Synthetic Rubber Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Propellants, non-motive (blowing agents) in Explosives Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
Chemical Identity
CAS21645-51-2
PubChem CID10176082
DTXSIDDTXSID2036405
FormulaAlH3O3
Mol. Weight78.004 g/mol
SMILES[OH-].[OH-].[OH-].[Al+3]
Data Sources
- EPA CompTox (DSSTox) · DTXSID2036405Retrieved 2026-04-06
- PubChem · compound 10176082Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Aluminum hydroxide (CAS 21645-51-2) https://chemicalindependence.com/chemical/21645-51-2/ EPA CompTox (DSSTox): DTXSID2036405. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID2036405 PubChem: 10176082. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/10176082 EPA Chemical Data Reporting: 21645-51-2. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 21645-51-2. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 281830 for CAS 21645-51-2. Reporting year: 2024. https://usatrade.census.gov/