2-Methylpropane-1,3-diol

Drug ingredient

CAS 2163-42-0

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$82M

Top sourceGermany 18%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290539 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 290539, which covers 48 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

DE 18%GermanyKR 16%South KoreaBR 11%BrazilTW 8%TaiwanMX 7%Mexico

Canada
Liechtenstein
Israel
Ireland
Portugal
Ukraine
Singapore

EPA-registered manufacturers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Lyondell Chemical

Proviron

Domestic parents -- activity not disclosed (5)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Chemical Distribution Network

Colonial Group

Parker-Hannifin

Soyventis North America

The Sherwin Williams

EPA-registered importers (4)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Dupont Specialty Products Usa

Everchem

Wego Chemical Group

Why It Matters

Sectors

HealthAgriculturePlastics & RubberConsumer ProductsPaints & CoatingsPaper & PrintingCore Chemicals

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Lesonel Forming Feminine WASH

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 8 sectors as 5 functional roles.

•Solvent in Printing Ink Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Intermediate in Plastics Product Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Intermediate in Wholesale and Retail Trade (15%)Processing—repackaging
•Solvent in Paint and Coating Manufacturing (30%)Processing—incorporation into formulation, mixture, or reaction product
•Intermediate in Plastics Material and Resin Manufacturing (51%)Processing as a reactant
•Soil amendments (fertilizers) in Agriculture, Forestry, Fishing and Hunting (4%)Processing—incorporation into formulation, mixture, or reaction product
•Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Binder in Plastics Material and Resin Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Waterproofing agent in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.02/gAaron Chemicals LLC

CountryHong Kong

Pack$8.00 / 500 g

Purity95%

Vendors21 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

20 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.02	1 kg	95%
BLD Pharmatech GmbH	Germany	$0.05	1 kg	95%
BLD Pharmatech Ltd.	China	$0.05	1 kg	95%
Fluorochem EU	Germany	$0.07	500 g	95%
ALFA AESAR	Germany	$0.07	2.5 kg	98%
A2B Chem LLC	United States	$0.08	500 g	95%
AA BLOCKS	United States	$0.10	500 g	95%
Ambeed, Inc.	United States	$0.13	500 g	95%
AK Scientific Specialized	United States	$0.15	500 g	95%
Synthonix	United States	$0.16	500 g	95%
AK Scientific, Inc.	United States	$0.19	500 g	99%
BLD Pharmatech Co., Limited	United States	$0.21	100 g	95%
Combi-Blocks, Inc.	United States	$0.25	1 kg	98%
Angene International Limited	United States	$0.30	500 g	95%
Fluorochem UK	United Kingdom	$0.34	25 g	95%
AstaTech (2 weeks)	United States	$0.99	100 g	95%
Labotest KG	Germany	$453.00	1000 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	95%
Asinex	Netherlands	$6461.40	100 mg	90%
TimTec, LLC (back-ordered)	United States	$32000.00	15 mg	94%

Chemical Identity

CAS2163-42-0

PubChem CID75103

DTXSIDDTXSID3029231

FormulaC4H10O2

Mol. Weight90.12 g/mol

SMILESCC(CO)CO

Data Sources

EPA CompTox (DSSTox) · DTXSID3029231Retrieved 2026-04-06
PubChem · compound 75103Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

2-Methylpropane-1,3-diol (CAS 2163-42-0) https://chemicalindependence.com/chemical/2163-42-0/ EPA CompTox (DSSTox): DTXSID3029231. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID3029231 PubChem: 75103. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/75103 EPA Chemical Data Reporting: 2163-42-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 2163-42-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290539 for CAS 2163-42-0. Reporting year: 2024. https://usatrade.census.gov/