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Oxaprozin

Drug ingredient

CAS 21256-18-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 21256-18-8
US productionNot reported
Import value, 2024$6.4B
Top sourceSingapore 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293499 · basket

These shares come from HS customs code 293499, which covers 575 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
SG 36%SingaporeIE 23%IrelandCN 11%ChinaCH 6%SwitzerlandIN 5%India
12 FDA-registered drug labelers
Amneal Pharmaceuticals NY LLC
Ayurax, LLC
B.V. KATWIJK CHEMIE
Bryant Ranch Prepack
Chartwell RX, LLC.
Direct_Rx
Dr. Reddy's Laboratories Limited
Pfizer Laboratories Div Pfizer Inc
Proficient Rx LP
SOLA Pharmaceuticals, LLC
Solubiomix, LLC
ST MARY'S MEDICAL PARK PHARMACY

Why It Matters

Sectors
Health
Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

  • •Daypro
  • •Oxaprozin
  • •Coxanto
FDA Shortage Status
No Shortage
Shortage History
  • to be discontinued

    Oxaprozin Tablet

    Shortage listed since July 17, 2025

See all current drug shortages

Vendor Pricing

$0.34/gAaron Chemicals LLC
CountryHong Kong
Pack$168.00 / 500 g
Purity98%
Vendors31 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

30 more vendors
VendorCountry$/gPackPurity
Angene ChemicalChina → Hong Kong$0.36500 g98%
Combi-Blocks, Inc.United States$0.48500 g98%
A2B Chem LLCUnited States$0.52500 g98%
ChemsceneUnited States$0.55500 g—
BLD Pharmatech Co., LimitedUnited States$0.56500 g99%
BLD Pharmatech GmbHGermany$0.56500 g99%
BLD Pharmatech Ltd.China$0.56500 g99%
Ambeed, Inc.United States$0.56500 g99%
AA BLOCKSUnited States$0.64100 g98%
Fulfilled by MolportLatvia$1.005 g99%
AK Scientific SpecializedUnited States$1.10100 g95%
Fluorochem EUGermany$1.1625 g98%
AK Scientific, Inc.United States$1.47100 g98%
Fluorochem UKUnited Kingdom$2.005 g98%
Angene International LimitedUnited States$2.61100 g98%
AstaTech, IncUnited States$9.4025 g95%
Apollo Scientific UKUnited Kingdom$10.8025 g98%
Maybridge, Ltd.United Kingdom$20.835 g97%
MedKoo Biosciences, IncUnited States$125.0010 g98%
TargetMol ChemicalsChina → United States$198.001 g99.02%
TargetMol Chemicals USUnited States$270.00500 mg99.02%
MedChemExpress MCESweden$411.40500 mg99.94%
TargetMol Chemicals EUAustria$680.00100 mg99.02%
Apexbio Technology LLCUnited States$1360.0050 mg98.75%
Axon MedchemNetherlands$1920.0050 mg99%
Sigma-Aldrich (Rush Stock)Germany$2610.40200 mg—
Sigma-AldrichGermany$2610.40200 mg—
Cayman EuropeEstonia$3712.8050 mg98%
AngeneChina → Hong Kong$4266.6730 mg98%
Key Organics Ltd.United Kingdom$6900.0010 mg97%

Chemical Identity

CAS21256-18-8
PubChem CID4614
DTXSIDDTXSID1045118
FormulaC18H15NO3
Mol. Weight293.3 g/mol
SMILESC1=CC=C(C=C1)C2=C(OC(=N2)CCC(=O)O)C3=CC=CC=C3

Data Sources

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Brief citations

Oxaprozin (CAS 21256-18-8) https://chemicalindependence.com/chemical/21256-18-8/ PubChem: 4614. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/4614 FDA National Drug Code directory: CAS 21256-18-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 21256-18-8. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293499 for CAS 21256-18-8. Reporting year: 2024. https://usatrade.census.gov/