Methyl 2-hydroxy-2-methylpropionate

CAS 2110-78-3

EPA’s 2023 records show zero U.S. production of this chemical.

US productionZero

Import value, 2024$81M

Import volumeCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Top sourceChina 35%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291819 · basket

EPA reports by year

2023: US production Zero · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 291819, which covers 96 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 35%ChinaIN 34%IndiaIT 9%ItalyDE 9%GermanyJP 4%Japan

Switzerland
Ukraine
Colombia
Taiwan
Belgium
Israel
Sweden
Hungary
Ireland
Slovakia

EPA-registered importers (3)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Sumitomo Chemical · JP Japan

Samsung Austin Semiconductor

Sumitomo Chemical Advanced Technologies

Why It Matters

Sectors

Electronics

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 1 sector as 2 functional roles.

•Drier in Computer and Electronic Product Manufacturing (100%)Processing as a reactant
•Cleaning agent in Computer and Electronic Product Manufacturing (100%)Use—non-incorporative activities

Vendor Pricing

$0.08/gAaron Chemicals LLC

CountryHong Kong

Pack$40.00 / 500 g

Purity97%

Vendors11 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

10 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.09	500 g	97%
Fluorochem UK	United Kingdom	$0.26	100 g	95%
AK Scientific, Inc.	United States	$0.34	1 kg	98%
Combi-Blocks, Inc.	United States	$0.34	1 kg	98%
AK Scientific Specialized	United States	$0.35	500 g	95%
A2B Chem LLC	United States	$0.36	1 kg	98%
AA BLOCKS	United States	$0.39	1 kg	98%
Ambeed, Inc.	United States	$1.57	100 g	98%
Angene International Limited	United States	$3.20	25 g	98%
Angene	China → Hong Kong	$4266.67	30 mg	97%

Chemical Identity

CAS2110-78-3

PubChem CID75024

DTXSIDDTXSID5062184

FormulaC5H10O3

Mol. Weight118.13 g/mol

SMILESCC(C)(C(=O)OC)O

Data Sources

EPA CompTox (DSSTox) · DTXSID5062184Retrieved 2026-04-06
PubChem · compound 75024Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Methyl 2-hydroxy-2-methylpropionate (CAS 2110-78-3) https://chemicalindependence.com/chemical/2110-78-3/ EPA CompTox (DSSTox): DTXSID5062184. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID5062184 PubChem: 75024. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/75024 EPA Chemical Data Reporting: 2110-78-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 2110-78-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291819 for CAS 2110-78-3. Reporting year: 2024. https://usatrade.census.gov/