Darunavir

Drug ingredient

CAS 206361-99-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$2.0B

Top sourceIreland 63%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland

Portugal
Spain
Italy
Austria
Israel
Hungary
Canada
South Korea
Netherlands
Finland
Poland
Indonesia
Ukraine
Mexico
South Africa
Croatia
Greece
Taiwan
Hong Kong

15 FDA-registered drug labelers

Amneal Pharmaceuticals NY LLC

Aurobindo Pharma Limited

Bryant Ranch Prepack

Camber Pharmaceuticals, Inc.

Cipla Ltd.

Dr.Reddys Laboratories Inc

Hetero Labs Limited

Honour Lab Limited

Janssen Products LP

LAURUS LABS LIMITED

MSN Life Sciences Private Limited

Novadoz Pharmaceuticals LLC

Patheon Inc.

Viona Pharmaceuticals Inc

Zydus Lifesciences Limited

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Darunavir
•Symtuza

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS206361-99-1

PubChem CID213039

DTXSIDDTXSID0046779

FormulaC27H37N3O7S

Mol. Weight547.7 g/mol

SMILESCC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2COC3C2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N

Data Sources

PubChem · compound 213039Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Darunavir (CAS 206361-99-1) https://chemicalindependence.com/chemical/206361-99-1/ PubChem: 213039. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/213039 FDA National Drug Code directory: CAS 206361-99-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293590 for CAS 206361-99-1. Reporting year: 2024. https://usatrade.census.gov/