Amifostine

Drug ingredient

CAS 20537-88-6

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$760M

Top sourceChina 33%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293090 · basket

These shares come from HS customs code 293090, which covers 418 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 33%ChinaES 14%SpainCH 9%SwitzerlandIT 7%ItalyIN 7%India

Israel
Croatia
Ukraine
Slovakia
United Arab Emirates
Ireland
Poland
Lithuania
Brazil
Singapore
Australia
Armenia
Hong Kong
Vietnam
Czech Republic
Hungary
Greece
Russia

7 FDA-registered drug labelers

Farmabios S.p.A.

Legacy Pharma USA Inc.

Lianyungang Runzhong Pharmaceutical Co. Ltd.

SUN PHARMACEUTICAL INDUSTRIES, INC.

Symbiosis Pharmaceutical Services Limited

W. R. Grace & Co.-Conn.

Zach System S.A.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Ethyol

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$760.00/gCombi-Blocks, Inc.

CountryUnited States

Pack$760.00 / 1 g

Purity95%

Vendors18 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

17 more vendors

Vendor	Country	$/g	Pack	Purity
BLD Pharmatech Ltd.	China	$865.00	1 g	98%
A2B Chem LLC	United States	$955.00	200 mg	99.91%
AA BLOCKS	United States	$1090.00	200 mg	98%
Aaron Chemicals LLC	Hong Kong	$1224.00	250 mg	98%
TargetMol Chemicals	China → United States	$1235.00	200 mg	99.91%
Angene Chemical	China → Hong Kong	$1236.00	250 mg	98%
BLD Pharmatech Co., Limited	United States	$1296.00	250 mg	98%
Ambeed, Inc.	United States	$1296.00	250 mg	98%
Molnova	China	$1432.00	500 mg	99%
TargetMol Chemicals EU	Austria	$1760.00	100 mg	99.91%
MedChemExpress MCE	Sweden	$1875.50	200 mg	99.95%
AstaTech, Inc	United States	$2876.00	500 mg	97%
Apexbio Technology LLC	United States	$4000.00	50 mg	98.44%
AK Scientific, Inc.	United States	$4240.00	100 mg	98%
Angene International Limited	United States	$4552.00	500 mg	98%
MedKoo Biosciences, Inc	United States	$13500.00	50 mg	98%
TimTec, LLC	United States	$14666.67	30 mg	90%

Chemical Identity

CAS20537-88-6

PubChem CID2141

DTXSIDDTXSID8022585

FormulaC5H15N2O3PS

Mol. Weight214.23 g/mol

SMILESC(CN)CNCCSP(=O)(O)O

Data Sources

PubChem · compound 2141Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Amifostine (CAS 20537-88-6) https://chemicalindependence.com/chemical/20537-88-6/ PubChem: 2141. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/2141 FDA National Drug Code directory: CAS 20537-88-6. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293090 for CAS 20537-88-6. Reporting year: 2024. https://usatrade.census.gov/