N,N-Dimethylacetoacetamide

CAS 2044-64-6

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$371M

Top sourceChina 27%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292419 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 292419, which covers 211 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 27%ChinaIN 18%IndiaDE 14%GermanyIT 10%ItalyGB 6%United Kingdom

Hungary
Austria
Spain
Egypt
Canada
Sweden
Ukraine
Denmark
Israel
Lithuania
Greece
Ireland
Taiwan
Uruguay
Turkey
Australia
Singapore
Latvia
Colombia

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Eastman Chemical

EPA-registered importers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Aoc

Arxada

Why It Matters

Sectors

Plastics & RubberCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Catalyst in Plastics Product Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.30/gA2B Chem LLC

CountryUnited States

Pack$150.00 / 500 g

Purity97%

Vendors9 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

8 more vendors

Vendor	Country	$/g	Pack	Purity
Combi-Blocks, Inc.	United States	$0.30	500 g	97%
AA BLOCKS	United States	$0.35	500 g	97%
Fluorochem EU	Germany	$1.34	100 g	95%
Angene International Limited	United States	$1.53	100 g	95%
Fluorochem UK	United Kingdom	$1.66	25 g	95%
Otava, Ltd.	Ukraine	$2280.00	50 mg	95%
Otava, Ltd. (2 weeks)	Ukraine	$2724.00	50 mg	95%
Princeton BioMolecular Research (SC)	United States	$2900.00	100 mg	90%

Chemical Identity

CAS2044-64-6

PubChem CID16278

DTXSIDDTXSID8027454

FormulaC6H11NO2

Mol. Weight129.16 g/mol

SMILESCC(=O)CC(=O)N(C)C

Data Sources

EPA CompTox (DSSTox) · DTXSID8027454Retrieved 2026-04-06
PubChem · compound 16278Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

N,N-Dimethylacetoacetamide (CAS 2044-64-6) https://chemicalindependence.com/chemical/2044-64-6/ EPA CompTox (DSSTox): DTXSID8027454. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID8027454 PubChem: 16278. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/16278 EPA Chemical Data Reporting: 2044-64-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 2044-64-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292419 for CAS 2044-64-6. Reporting year: 2024. https://usatrade.census.gov/