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amiloride hydrochloride anhydrous

Drug ingredient

CAS 2016-88-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 2016-88-8
1 HCl
US productionNot reported
Import value, 2024$1.4B
Top sourceIreland 33%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293399 · basket

These shares come from HS customs code 293399, which covers 518 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 33%IrelandCN 26%ChinaIN 11%IndiaDE 9%GermanyIT 4%Italy
3 FDA-registered drug labelers
Bryant Ranch Prepack
Endo USA, Inc.
Sigmapharm Laboratories, LLC

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Amiloride Hydrochloride
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS2016-88-8
PubChem CID16230
DTXSIDDTXSID2024452
FormulaC6H9Cl2N7O
Mol. Weight266.09 g/mol
SMILESC1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.Cl

Data Sources

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Brief citations

amiloride hydrochloride anhydrous (CAS 2016-88-8) https://chemicalindependence.com/chemical/2016-88-8/ PubChem: 16230. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/16230 FDA National Drug Code directory: CAS 2016-88-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293399 for CAS 2016-88-8. Reporting year: 2024. https://usatrade.census.gov/