sulfamethazine sodium

Drug ingredient

CAS 1981-58-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 1981-58-4 — 1 Na⁺

US productionNot reported

Import value, 2024$2.0B

Top sourceIreland 63%

EPA lists this chemical as inactive, meaning no company reported making, importing or processing it in the US from 2006 to 2016.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland

Portugal
Spain
Italy
Austria
Israel
Hungary
Canada
South Korea
Netherlands
Finland
Poland
Indonesia
Ukraine
Mexico
South Africa
Croatia
Greece
Taiwan
Hong Kong

2 FDA-registered drug labelers

Hunan Wugan Pharmaceutical Co., Ltd.

Hunan Xiangyikang Pharmaceutical Co., Ltd

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$0.11/gAaron Chemicals LLC

CountryHong Kong

Pack$56.00 / 500 g

Purity98%

Vendors11 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

10 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.13	500 g	98%
A2B Chem LLC	United States	$0.13	500 g	99%
BLD Pharmatech GmbH	Germany	$0.16	500 g	98%
BLD Pharmatech Ltd.	China	$0.16	500 g	98%
AA BLOCKS	United States	$0.17	500 g	99%
MedChemExpress MCE	Sweden	$12.58	5 g	99.9%
Angene International Limited	United States	$114.00	1 g	98%
Molnova	China	$980.00	50 mg	99%
Angene	China → Hong Kong	$4266.67	30 mg	98%
Key Organics Ltd.	United Kingdom	$6900.00	10 mg	98%

Chemical Identity

CAS1981-58-4

PubChem CID13456556

DTXSIDDTXSID70890551

FormulaC12H13N4NaO2S

Mol. Weight300.31 g/mol

SMILESCC1=CC(=NC(=N1)[N-]S(=O)(=O)C2=CC=C(C=C2)N)C.[Na+]

Data Sources

PubChem · compound 13456556Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

sulfamethazine sodium (CAS 1981-58-4) https://chemicalindependence.com/chemical/1981-58-4/ PubChem: 13456556. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/13456556 EPA TSCA Inventory: CAS 1981-58-4. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293590 for CAS 1981-58-4. Reporting year: 2024. https://usatrade.census.gov/