Lonafarnib

Drug ingredient

CAS 193275-84-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$1.3B

Top sourceChina 32%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293339 · basket

These shares come from HS customs code 293339, which covers 397 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 32%ChinaIN 15%IndiaDE 10%GermanyBE 9%BelgiumCH 8%Switzerland

Taiwan
Ukraine
Sweden
Argentina
Canada
Finland
Malta
Israel
Netherlands
Denmark
United Arab Emirates
Mexico
Brunei
Slovakia
Australia
South Africa
Poland
Latvia
Lithuania
Estonia
Slovenia
Czech Republic
Croatia
Hong Kong

3 FDA-registered drug labelers

Corden Pharma Colorado, Inc.

Lonza Bend Inc.

Sentynl Therapeutics, Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Zokinvy

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$2948.00/gAaron Chemicals LLC

CountryHong Kong

Pack$737.00 / 250 mg

Purity98%

Vendors22 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

21 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$2968.00	250 mg	98%
Combi-Blocks (back-ordered)	United States	$2980.00	250 mg	95%
BLD Pharmatech Ltd.	China	$3032.00	250 mg	98%
Ambeed, Inc.	United States	$3336.00	250 mg	98%
A2B Chem LLC	United States	$3490.00	100 mg	98%
Key Organics Ltd.	United Kingdom	$3742.86	35 mg	97%
AA BLOCKS	United States	$3880.00	100 mg	98%
BLD Pharmatech GmbH	Germany	$4460.00	100 mg	98%
BLD Pharmatech Co., Limited	United States	$4910.00	100 mg	98%
Molnova	China	$6240.00	100 mg	99%
TargetMol Chemicals	China → United States	$6930.00	100 mg	99.94%
Apexbio Technology LLC	United States	$9695.00	200 mg	98.97%
TargetMol Chemicals US	United States	$9940.00	50 mg	99.94%
MedChemExpress MCE	Sweden	$11253.00	100 mg	99.85%
MedKoo Biosciences, Inc	United States	$12500.00	100 mg	98%
TargetMol Chemicals EU	Austria	$12520.00	25 mg	99.94%
AstaTech (2 weeks)	United States	$18000.00	25 mg	99%
Cayman Europe	Estonia	$20039.60	25 mg	98%
Angene International Limited	United States	$20100.00	50 mg	98%
Sigma-Aldrich (Rush Stock)	Germany	$31455.60	25 mg	98%
Sigma-Aldrich	Germany	$31455.60	25 mg	98%

Chemical Identity

CAS193275-84-2

PubChem CID148195

DTXSIDDTXSID90172927

FormulaC27H31Br2ClN4O2

Mol. Weight638.8 g/mol

SMILESC1CN(CCC1CC(=O)N2CCC(CC2)C3C4=C(CCC5=C3N=CC(=C5)Br)C=C(C=C4Br)Cl)C(=O)N

Data Sources

PubChem · compound 148195Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Lonafarnib (CAS 193275-84-2) https://chemicalindependence.com/chemical/193275-84-2/ PubChem: 148195. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/148195 FDA National Drug Code directory: CAS 193275-84-2. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293339 for CAS 193275-84-2. Reporting year: 2024. https://usatrade.census.gov/