Metolazone

Drug ingredient

CAS 17560-51-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$2.0B

Top sourceIreland 63%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland

Portugal
Spain
Italy
Austria
Israel
Hungary
Canada
South Korea
Netherlands
Finland
Poland
Indonesia
Ukraine
Mexico
South Africa
Croatia
Greece
Taiwan
Hong Kong

25 FDA-registered drug labelers

A-S Medication Solutions

Aarkish Pharmaceuticals NJ Inc.

Advagen Pharma Limited

Alembic Pharmaceuticals Inc.

Alembic Pharmaceuticals Limited

American Health Packaging

Amici Pharma, Inc

Aphena Pharma Solutions - Tennessee, LLC

Azico Biophore India Private Limited

Bryant Ranch Prepack

Centaur Pharmaceuticals Private Limited

Curia New York, Inc.

Golden State Medical Supply, Inc.

Ingenus Pharmaceuticals LLC

Major Pharmaceuticals

Marlex Pharmaceuticals, Inc.

Method Pharmaceuticals, LLC

Micro Labs Limited

MSN Life Sciences Private Limited

Mylan Institutional Inc.

Mylan Pharmaceuticals Inc.

Safecor Health LLC

Sandoz Inc

Siegfried Evionnaz SA

Unichem Pharmaceuticals (USA), Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Metolazone

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$585.00/gAstaTech, Inc

CountryUnited States

Pack$585.00 / 1 g

Purity95%

Vendors14 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

13 more vendors

Vendor	Country	$/g	Pack	Purity
A2B Chem LLC	United States	$610.00	1 g	98%
AA BLOCKS	United States	$675.00	1 g	98%
TargetMol Chemicals	China → United States	$960.00	50 mg	99.79%
MedChemExpress MCE	Sweden	$1125.30	100 mg	99.68%
Apexbio Technology LLC	United States	$1360.00	50 mg	99.5%
Molnova	China	$1540.00	50 mg	99%
Sigma-Aldrich (Rush Stock)	Germany	$2610.40	200 mg	—
Sigma-Aldrich	Germany	$2610.40	200 mg	—
Cayman Europe	Estonia	$2665.60	100 mg	98%
MedKoo Biosciences, Inc	United States	$3400.00	250 mg	98%
Axon Medchem	Netherlands	$3840.00	50 mg	99%
AK Scientific, Inc.	United States	$4290.00	100 mg	98%
Key Organics Ltd.	United Kingdom	$6900.00	10 mg	98%

Chemical Identity

CAS17560-51-9

PubChem CID4170

DTXSIDDTXSID6045167

FormulaC16H16ClN3O3S

Mol. Weight365.8 g/mol

SMILESCC1NC2=CC(=C(C=C2C(=O)N1C3=CC=CC=C3C)S(=O)(=O)N)Cl

Data Sources

PubChem · compound 4170Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Metolazone (CAS 17560-51-9) https://chemicalindependence.com/chemical/17560-51-9/ PubChem: 4170. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/4170 FDA National Drug Code directory: CAS 17560-51-9. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293590 for CAS 17560-51-9. Reporting year: 2024. https://usatrade.census.gov/